PYRAZOLIDINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C3H8N2
Molecular Weight	72.109
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C1CNNC1

InChI

InChIKey=USPWKWBDZOARPV-UHFFFAOYSA-N

InChI=1S/C3H8N2/c1-2-4-5-3-1/h4-5H,1-3H2

HIDE SMILES / InChI

Molecular Formula	C3H8N2
Molecular Weight	72.109
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Asymmetric intramolecular [3 + 2] cycloaddition reactions of acylhydrazones/olefins using a chiral zirconium catalyst.	2002 Nov 20	12431089
Cu- and Pd-catalyzed asymmetric one-pot tandem addition-cyclization reaction of 2-(2',3'-alkadienyl)-beta-keto esters, organic halides, and dibenzyl azodicarboxylate: an effective protocol for the enantioselective synthesis of pyrazolidine derivatives.	2004 Jun 24	15200318
Zirconium-catalyzed enantioselective [3+2] cycloaddition of hydrazones to olefins leading to optically active pyrazolidine, pyrazoline, and 1,3-diamine derivatives.	2004 Sep 15	15355109
Pyrazolidine derivatives with heteroaryl urea as dipeptidyl peptidase IV inhibitors.	2005 Aug	16079547
Metabolism, pharmacokinetics, tissue distribution, and excretion of [14C]CP-424391 in rats.	2005 Jan	15486077
Inhibition of dipeptidyl peptidase IV by novel inhibitors with pyrazolidine scaffold.	2005 Jul 1	15893294
Synthesis and antibacterial activity of dihydro-1,2-oxazine and 2-pyrazoline oxazolidinones: novel analogs of linezolid.	2005 Jun 2	15911264
Synthesis and evaluation of pyrazolidine derivatives as dipeptidyl peptidase IV (DP-IV) inhibitors.	2005 Mar 1	15713382
Stereoselective palladium-catalyzed four-component cascade synthesis of pyrrolidinyl-, pyrazolidinyl-, and isoxazolidinyl isoquinolines.	2005 Nov 25	16247817
Specialist gelator for ionic liquids.	2005 Nov 8	16262296
Aqueous N-heterocyclization of primary amines and hydrazines with dihalides: microwave-assisted syntheses of N-azacycloalkanes, isoindole, pyrazole, pyrazolidine, and phthalazine derivatives.	2006 Jan 6	16388628
Highly diastereoselective palladium-catalyzed cyclizations of 3,4-allenylic hydrazines and organic halides -- highly stereoselective synthesis of optically active pyrazolidine derivatives and the prediction of the stereoselectivity.	2007	17696188
2'-(4-Chlorophenyl)-2,3,4,5,6,7-hexahydro-4',7'-methanospiro[9H-fluorene-9,3'-1H-indazole]-1'-carbonitrile and methyl 4'-chloro-2'-(4-chlorophenyl)-1'-cyanospiro[9H-fluorene-9,3'-pyrazolidine]-4'-carboxylate.	2007 Dec	18057628
GaCl(3)-catalyzed insertion of diazene derivatives into the cyclopropane ring.	2007 Sep 28	17824644
Regioselective synthesis of 1,3,5-tri- and 1,3,4,5-tetrasubstituted pyrazoles from N-arylhydrazones and nitroolefins.	2008 Mar 21	18278943
Stereoselective synthesis of cis- or trans-3,5-disubstituted pyrazolidines via Pd-catalyzed carboamination reactions: use of allylic strain to control product stereochemistry through N-substituent manipulation.	2008 Oct 1	18774811
5-(3-Fluoro-phen-yl)-1-phenyl-pyrazolidin-3-one.	2008 Sep 6	21201098
Efficient air-stable organometallic low-molecular-mass gelators for ionic liquids: synthesis, aggregation and application of pyridine-bridged bis(benzimidazolylidene)-palladium complexes.	2009	19123219
Skeletally diverse small molecules using a build/couple/pair strategy.	2009 Apr 2	19275223
Synthesis and properties of chiral pyrazolidines derived from (+)-pulegone.	2010 Jul 5	20496356

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:45:27 GMT 2023` Edited by `admin` on `Fri Dec 15 19:45:27 GMT 2023`
Record UNII	Y0MA3161MR
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PYRAZOLIDINE

Systematic Name

English

Code System Code Type Description

PUBCHEM

79033