Obrixtamig

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 05:34:14 GMT 2025` Edited by `admin` on `Wed Apr 02 05:34:14 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type
Sequence Origin	HUMANIZED
Record UNII	Y09G7LIC1A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Obrixtamig

Official Name

English

BI-764532

Preferred Name

English

L-kappa-H-gamma1 (knob) chain anti-DLL3 (1-705) [L-kappa anti-DLL3 (1-214) [V-KAPPA (Homo sapiens IGKV1-17*03 (94.9%) -IGKJ2*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1-107) -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')] -

Common Name

English

immunoglobulin L-kappa-H-gamma1_L-lambda-H-gamma1, anti-[Homo sapiens DLL3 (delta-like ligand 3, delta like canonical Notch ligand 3)] and anti-[Homo sapiens CD3E (CD3 epsilon, Leu-4)], bispecific

Common Name

English

Immunoglobulin, bispecific, anti-(human CD3 antigen) (human-Mus musculus monoclonal BI 764532 ?-chain) fusion protein with peptide linker (38-amino acid) fusion protein with immunoglobulin G1 [242-alanine,243-alanine,374-serine,376-alanine,415-valine,443

Common Name

English

obrixtamig [INN]

Common Name

English

BI764532

Code

English

Code System Code Type Description

NCI_THESAURUS

C177765