FERRIC CHLORIDE DIHYDRATE

First approved in 1957

Details

Stereochemistry	ACHIRAL
Molecular Formula	3Cl.Fe.2H2O
Molecular Weight	198.235
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O.O.[Cl-].[Cl-].[Cl-].[Fe+3]

InChI

InChIKey=IJIVUROORPGPBF-UHFFFAOYSA-K

InChI=1S/3ClH.Fe.2H2O/h3*1H;;2*1H2/q;;;+3;;/p-3

HIDE SMILES / InChI

Molecular Formula	HO
Molecular Weight	17.0073
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Fe
Molecular Weight	55.845
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/27995746 | http://onlinelibrary.wiley.com/doi/10.1002/047084289X.rn01568/abstract?userIsAuthenticated=false&deniedAccessCustomisedMessage=https://www.ncbi.nlm.nih.gov/pubmed/27684194 | https://www.ncbi.nlm.nih.gov/pubmed/17511797 | https://www.ncbi.nlm.nih.gov/pubmed/1427505https://books.google.ru/books?id=3hLmyma2-MsC&pg=PA241&lpg=PA241&dq=FERRIC+AMMONIUM+CHLORIDE retrieved from A Consumer's Dictionary of Cosmetic Ingredients, 7th Edition: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics and Cosmeceuticals By Ruth Winter

Iron compound. Used as a styptic and astringent.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2596
Parenteral Nutrition 10 Sources: https://www.hpra.ie/img/uploaded/swedocuments/2124555.PA0566_015_002.9e9eecde-fb07-4612-8f14-39d5233b7ace.000001Product%20Leaflet%20Approved.150327.pdf https://www.ncbi.nlm.nih.gov/pubmed/20377770	Primary	Approved 8583	Additrace N Approved Use A source of electrolytes and trace elements as an integral part of a complete intravenous nutritional regimen, for adults and children over 40 kg.
Iron deficiency 41 Sources: https://www.ncbi.nlm.nih.gov/pubmed/17511797	Preventing	Approved 8583	Parmirin Approved Use Preventive treatment of iron deficiency
Unknown 2596
Chronic kidney disease 55 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=237da26c-f38c-4faa-93ad-735e71c9d0c1	Palliative	Approved 8583	VELPHORO Approved Use Velphoro is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis. Launch Date 2013

PubMed

Title	Date	PubMed
A Simplified Fe-Based PhotoATRP Using Only Monomers and Solvent.	2017-07	27995746
Effect of iron and carbon monoxide on fibrinogenase-like degradation of plasmatic coagulation by venoms of four Crotalus species.	2017-01	26845427
Ferric Chloride-induced Murine Thrombosis Models.	2016-09-05	27684194
Halide Influence on Molecular and Supramolecular Arrangements of Iron Complexes with a 3,5-Bis(2-Pyridyl)-1,2,4,6-Thiatriazine Ligand.	2016-06-06	27152549
Iron-Catalyzed Regioselective Transfer Hydrogenative Couplings of Unactivated Aldehydes with Simple Alkenes.	2016-05-17	27072872
Mechanisms and origins of the switchable regioselectivity of FeBr3-catalyzed [1,2]-aryl and [1,2]-alkyl shifts of α-aryl aldehydes.	2016-02-28	26822257
Nazarov cyclization of 1,4-pentadien-3-ols: preparation of cyclopenta[b]indoles and spiro[indene-1,4'-quinoline]s.	2016-02-14	26771024
Oxidative aromatic C-N bond formation: convenient synthesis of N-amino-3-nitrile-indoles via FeBr3-mediated intramolecular cyclization.	2011-05-21	21451828
Metal-mediated cyclization of aryl and benzyl glycidyl ethers: a complete scenario.	2008-12-17	19053452

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Various alkyl aldehydes with linear alkyl chains were highly reactive under these conditions and afforded the corresponding products in good to excellent yields in the presence of 1 or 5 mol% of FeBr3 (Ferric bromide).

Substance Class	Chemical Created by `admin` on `Mon Mar 31 20:12:07 GMT 2025` Edited by `admin` on `Mon Mar 31 20:12:07 GMT 2025`
Record UNII	Y048945596
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FERRIC CHLORIDE DIHYDRATE

Common Name

English

IRON CHLORIDE (FECL3), DIHYDRATE

Preferred Name

English

IRON TRICHLORIDE DIHYDRATE

Systematic Name

English

Code System Code Type Description

PUBCHEM

91618179