Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C11H12N2O3.H2O |
| Molecular Weight | 238.2399 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.NC(CC1=CNC2=C1C=C(O)C=C2)C(O)=O
InChI
InChIKey=UIHHMHBYEZJGNC-UHFFFAOYSA-N
InChI=1S/C11H12N2O3.H2O/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10;/h1-2,4-5,9,13-14H,3,12H2,(H,15,16);1H2
| Molecular Formula | C11H12N2O3 |
| Molecular Weight | 220.2246 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
| Molecular Formula | H2O |
| Molecular Weight | 18.0153 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DescriptionSources: DOI: 10.1016/S0079-6123(08)60124-7Curator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/3128339
Sources: DOI: 10.1016/S0079-6123(08)60124-7
Curator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/3128339
DL-5-hydroxytryptophan, 5-HTP is a serotonin precursor. It was discovered on the rats, that the pharmacological responses and changes in brain 5-hydroxytryptamine (5-HT) concentration elicited following the administration of 5-HTP did not reflect changes in the concentration of endogenous brain 5-HT. The biochemical and pharmacological properties of the 5-HTP-induced increases in brain 5-HT concentration were distinctly different from those of increases in the endogenous content of the amine. In normal rats, administered 5-HTP, observable pharmacological responses were not elicited, despite equal or even larger increases in brain 5-HT concentration.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The effect of DL-5-hydroxytryptophan (5-HTP) on plasma prolactin in pituitary stalk sectioned rats. | 1981-08 |
|
| The effects of DL-5-hydroxytryptophan on ethanol consumption by rats. | 1978-04 |
|
| DL-5-hydroxytryptophan-induced changes in central monoamine neurons after peripheral decarboxylase inhibition. | 1971-06 |
|
| The oxytocic activity of DL-5-hydroxytryptophan. | 1961-09 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 17:47:07 GMT 2025
by
admin
on
Mon Mar 31 17:47:07 GMT 2025
|
| Record UNII |
XXE58DJG85
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
XXE58DJG85
Created by
admin on Mon Mar 31 17:47:07 GMT 2025 , Edited by admin on Mon Mar 31 17:47:07 GMT 2025
|
PRIMARY | |||
|
10030-79-2
Created by
admin on Mon Mar 31 17:47:07 GMT 2025 , Edited by admin on Mon Mar 31 17:47:07 GMT 2025
|
PRIMARY | |||
|
45052530
Created by
admin on Mon Mar 31 17:47:07 GMT 2025 , Edited by admin on Mon Mar 31 17:47:07 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
PARENT -> SALT/SOLVATE | |||
|
ANHYDROUS->SOLVATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |