Details
Stereochemistry | RACEMIC |
Molecular Formula | C11H12N2O3.H2O |
Molecular Weight | 238.2399 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
O.NC(CC1=CNC2=C1C=C(O)C=C2)C(O)=O
InChI
InChIKey=UIHHMHBYEZJGNC-UHFFFAOYSA-N
InChI=1S/C11H12N2O3.H2O/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10;/h1-2,4-5,9,13-14H,3,12H2,(H,15,16);1H2
Molecular Formula | H2O |
Molecular Weight | 18.0153 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | C11H12N2O3 |
Molecular Weight | 220.2246 |
Charge | 0 |
Count |
|
Stereochemistry | RACEMIC |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Optical Activity | ( + / - ) |
DescriptionSources: DOI: 10.1016/S0079-6123(08)60124-7Curator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/3128339
Sources: DOI: 10.1016/S0079-6123(08)60124-7
Curator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/3128339
DL-5-hydroxytryptophan, 5-HTP is a serotonin precursor. It was discovered on the rats, that the pharmacological responses and changes in brain 5-hydroxytryptamine (5-HT) concentration elicited following the administration of 5-HTP did not reflect changes in the concentration of endogenous brain 5-HT. The biochemical and pharmacological properties of the 5-HTP-induced increases in brain 5-HT concentration were distinctly different from those of increases in the endogenous content of the amine. In normal rats, administered 5-HTP, observable pharmacological responses were not elicited, despite equal or even larger increases in brain 5-HT concentration.
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/307265
for rats: DL-5-hydroxytryptophan (5HTP) in doses of 50, 100 or 200 mg/kg was injected intraperitoneally one hour prior to the drinking session.
Route of Administration:
Intraperitoneal
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:07:12 GMT 2023
by
admin
on
Fri Dec 15 15:07:12 GMT 2023
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Record UNII |
XXE58DJG85
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Record Status |
Validated (UNII)
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Record Version |
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10030-79-2
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45052530
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admin on Fri Dec 15 15:07:12 GMT 2023 , Edited by admin on Fri Dec 15 15:07:12 GMT 2023
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Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE | |||
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ANHYDROUS->SOLVATE |
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ACTIVE MOIETY |