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Details

Stereochemistry ACHIRAL
Molecular Formula C19H28ClN3O4
Molecular Weight 397.896
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ABT-224

SMILES

CCCCOC(=O)CN1CCC(CC1)NC(=O)C2=CC(Cl)=C(N)C=C2OC

InChI

InChIKey=AQMLPMSSCWTNNN-UHFFFAOYSA-N
InChI=1S/C19H28ClN3O4/c1-3-4-9-27-18(24)12-23-7-5-13(6-8-23)22-19(25)14-10-15(20)16(21)11-17(14)26-2/h10-11,13H,3-9,12,21H2,1-2H3,(H,22,25)

HIDE SMILES / InChI

Molecular Formula C19H28ClN3O4
Molecular Weight 397.896
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors in prefrontal cortical pyramidal neurons by a novel allosteric potentiator.
2001 Jul
Survival signaling and selective neuroprotection through glutamatergic transmission.
2002 Mar
Preliminary experience with an ampakine (CX516) as a single agent for the treatment of schizophrenia: a case series.
2002 Oct 1
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 11:14:58 GMT 2023
Edited
by admin
on Sat Dec 16 11:14:58 GMT 2023
Record UNII
XVR3JT7PGA
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ABT-224
Code English
4-(4-AMINO-5-CHLORO-2-METHOXYBENZAMIDO)PIPERIDINE-1-ACETIC ACID BUTYL ESTER
Systematic Name English
BUTYL 2-(4-((4-AMINO-5-CHLORO-2-METHOXY-BENZOYL)AMINO)-1-PIPERIDYL)ACETATE
Systematic Name English
ABT224
Code English
1-PIPERIDINEACETIC ACID, 4-((4-AMINO-5-CHLORO-2-METHOXYBENZOYL)AMINO)-, BUTYL ESTER
Systematic Name English
AU-224
Code English
Code System Code Type Description
CAS
287399-47-7
Created by admin on Sat Dec 16 11:14:58 GMT 2023 , Edited by admin on Sat Dec 16 11:14:58 GMT 2023
PRIMARY
FDA UNII
XVR3JT7PGA
Created by admin on Sat Dec 16 11:14:58 GMT 2023 , Edited by admin on Sat Dec 16 11:14:58 GMT 2023
PRIMARY
PUBCHEM
9822171
Created by admin on Sat Dec 16 11:14:58 GMT 2023 , Edited by admin on Sat Dec 16 11:14:58 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY