CLONIXERIL

Details

Stereochemistry	RACEMIC
Molecular Formula	C16H17ClN2O4
Molecular Weight	336.77
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=C(NC2=C(C=CC=N2)C(=O)OCC(O)CO)C=CC=C1Cl

InChI

InChIKey=SWYJYGCPTGKBDS-UHFFFAOYSA-N

InChI=1S/C16H17ClN2O4/c1-10-13(17)5-2-6-14(10)19-15-12(4-3-7-18-15)16(22)23-9-11(21)8-20/h2-7,11,20-21H,8-9H2,1H3,(H,18,19)

HIDE SMILES / InChI

Molecular Formula	C16H17ClN2O4
Molecular Weight	336.77
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/22723 https://patents.google.com/patent/CH534129A/de

Clonixeril is a glyceryl ester of a nonsteroid anti-inflammatory drug clonixin, developed by Scherico Ltd in the 1970s. Oral administration of clonixeril delays the onset of castor oil-induced diarrhoea in rats.

Approval Year

PubMed

Title	Date	PubMed
Delay of castor oil diarrhoea in rats: a new way to evaluate inhibitors of prostaglandin biosynthesis.	1978 Jan	22723

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:13:48 GMT 2023` Edited by `admin` on `Sat Dec 16 16:13:48 GMT 2023`
Record UNII	XVF42I68OX
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CLONIXERIL

Official Name

English

2,3-Dihydroxypropyl 2-(3-chloro-O-toluidino)nicotinate

Systematic Name

English

clonixeril [INN]

Common Name

English

SCH-12707

Code

English

NSC-335504

Code

English

CLONIXERIL [USAN]

Common Name

English

SCH 12707

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C257