ITOLIZUMAB

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 00:40:39 GMT 2023` Edited by `admin` on `Sat Dec 16 00:40:39 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	XQQ2RHV14N
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ITOLIZUMAB

Official Name

English

EQ001

Code

English

Immunoglobulin G1, anti-(human antigen CD6) (human-mouse monoclonal T1h heavy chain), disulfide with human-mouse monoclonal T1h light chain, dimer

Common Name

English

Immunoglobulin G1-kappa, anti-[Homo sapiens CD6 (Tp120, T12)], humanized monoclonal antibody; gamma1 heavy chain (1-449) [humanized VH (Homo sapiens IGHV3-21*08 (83.70%) -(IGHD)-IGHJ5*01) [8.8.12] (1-119)-Homo sapiens IGHG1*01 (120-449)], (222-214')-disu

Common Name

English

EQ-001

Code

English

Itolizumab [WHO-DD]

Common Name

English

ITOLIZUMAB [USAN]

Common Name

English

itolizumab [INN]

Common Name

English

BMAB-600

Code

English

T1H

Code

English

Classification Tree Code System Code

FDA ORPHAN DRUG

646718

Created by admin on Sat Dec 16 00:40:39 GMT 2023 , Edited by admin on Sat Dec 16 00:40:39 GMT 2023

NCI_THESAURUS

C20401

Created by admin on Sat Dec 16 00:40:39 GMT 2023 , Edited by admin on Sat Dec 16 00:40:39 GMT 2023

FDA ORPHAN DRUG

676618

Created by admin on Sat Dec 16 00:40:39 GMT 2023 , Edited by admin on Sat Dec 16 00:40:39 GMT 2023

Code System Code Type Description

INN

9321

Created by admin on Sat Dec 16 00:40:39 GMT 2023 , Edited by admin on Sat Dec 16 00:40:39 GMT 2023

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WIKIPEDIA

ITOLIZUMAB

Created by admin on Sat Dec 16 00:40:39 GMT 2023 , Edited by admin on Sat Dec 16 00:40:39 GMT 2023

PRIMARY

CAS

1116433-11-4

Created by admin on Sat Dec 16 00:40:39 GMT 2023 , Edited by admin on Sat Dec 16 00:40:39 GMT 2023

PRIMARY

FDA UNII

XQQ2RHV14N

Created by admin on Sat Dec 16 00:40:39 GMT 2023 , Edited by admin on Sat Dec 16 00:40:39 GMT 2023

PRIMARY

NCI_THESAURUS

C95787

Created by admin on Sat Dec 16 00:40:39 GMT 2023 , Edited by admin on Sat Dec 16 00:40:39 GMT 2023

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USAN

KL-88

Created by admin on Sat Dec 16 00:40:39 GMT 2023 , Edited by admin on Sat Dec 16 00:40:39 GMT 2023

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ChEMBL

CHEMBL1743033

Created by admin on Sat Dec 16 00:40:39 GMT 2023 , Edited by admin on Sat Dec 16 00:40:39 GMT 2023

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EVMPD

SUB184388

Created by admin on Sat Dec 16 00:40:39 GMT 2023 , Edited by admin on Sat Dec 16 00:40:39 GMT 2023

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From	To
1_22	1_96
1_146	1_202
1_263	1_323
1_369	1_427
2_22	2_96
2_146	2_202
2_263	2_323
2_369	2_427
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_222	3_214
2_222	4_214
1_228	2_228
1_231	2_231

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_299
N	2_299

Related Record Type Details


					LG25NJ6UJX

T-CELL DIFFERENTIATION ANTIGEN CD6

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					XQQ2RHV14N

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL