CYCLIN E1-CDK2 COMPLEX

Substance Class	Protein Created by `admin` on `Wed Apr 02 08:17:27 GMT 2025` Edited by `admin` on `Wed Apr 02 08:17:27 GMT 2025`
Protein Type	ENZYME
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	XQ3S8XKC4N
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

CDK2/CYCLIN E1 COMPLEX

Preferred Name

English

CYCLIN E1-CDK2 COMPLEX

Common Name

English

CYCLIN E1/CDK2

Common Name

English

G1/S-SPECIFIC CYCLIN-E1-CYCLIN-DEPENDENT KINASE 2 COMPLEX

Common Name

English

Code System Code Type Description

FDA UNII

XQ3S8XKC4N

Created by admin on Wed Apr 02 08:17:27 GMT 2025 , Edited by admin on Wed Apr 02 08:17:27 GMT 2025

PRIMARY

Related Record Type Details


					MKS45S912B

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					2QD8YT8RWZ

INX-315

INHIBITOR -> TARGET

Comments:

Using the Nanosyn biochemical assay.

Qualification:

IC50

Amount:

Modification Type	Location Site	Location Type	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_77] [1_395]	SITE_SPECIFIC	THREONINE PHOSPHATE	3L4WX7B1EI
AMINO_ACID_SUBSTITUTION	[2_15] [2_19]	SITE_SPECIFIC	TYROSINE O-PHOSPHATE	2R86C98KDX
AMINO_ACID_SUBSTITUTION	[2_6]	SITE_SPECIFIC	N6-ACETYLLYSINE	470AD5VY1X
AMINO_ACID_SUBSTITUTION	[2_1]	SITE_SPECIFIC	N-ACETYLMETHIONINE	9J12WX5B6A
AMINO_ACID_SUBSTITUTION	[1_103] [1_387] [1_399]	SITE_SPECIFIC	DEXFOSFOSERINE	VI4F0K069V
AMINO_ACID_SUBSTITUTION	[2_14] [2_160]	SITE_SPECIFIC	THREONINE PHOSPHATE	3L4WX7B1EI

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL