Eciskafusp alfa

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 19:28:58 UTC 2023` Edited by `admin` on `Sat Dec 16 19:28:58 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY AND PEPTIDE FUSION PROTEIN
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	XPV3BT6FPY
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Eciskafusp alfa

Official Name

English

RG-6979

Code

English

eciskafusp alfa [INN]

Common Name

English

ECISKAFUSP ALFA [USAN]

Common Name

English

RO-7284755

Code

English

humanized immunoglobulin G1-kappa, anti-[Homo sapiens PDCD1 (programmed cell death protein 1, PD-1, PD1, CD279)], fused at the C-terminus of one heavy chain, via a (G4S)3 peptide linker with one interleukin 2 mutant chain, glycoform alfa: gamma1 heavy ch

Common Name

English

RO7284755

Code

English

Immunoglobulin G1 [237-alanine,238-alanine,332-glycine,357-cysteine,369-tryptophan,de-450-lysine], anti-(human programmed cell death protein 1) (human-Mus musculus γ1-chain) fusion protein with peptide linker (GGGGS)3 fusion protein with interleukin 2 [

Common Name

English

RG6979

Code

English

Code System Code Type Description

CAS

2649758-52-9

Created by admin on Sat Dec 16 19:28:58 UTC 2023 , Edited by admin on Sat Dec 16 19:28:58 UTC 2023

PRIMARY

FDA UNII

XPV3BT6FPY

Created by admin on Sat Dec 16 19:28:58 UTC 2023 , Edited by admin on Sat Dec 16 19:28:58 UTC 2023

PRIMARY

INN

12317

Created by admin on Sat Dec 16 19:28:58 UTC 2023 , Edited by admin on Sat Dec 16 19:28:58 UTC 2023

PRIMARY

USAN

LM-168

Created by admin on Sat Dec 16 19:28:58 UTC 2023 , Edited by admin on Sat Dec 16 19:28:58 UTC 2023

PRIMARY

From	To
1_22	1_96
1_428	1_522
1_569	2_22
2_96	4_23
2_223	2_229
1_147	1_203
2_232	2_264
2_324	2_352
2_370	2_428
3_92	3_138
3_198	3_218
1_223	3_23
1_229	2_147
1_232	2_203
1_264	1_324
1_357	1_370

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_300
N	2_300

Related Record Type Details


					938DNF64FO

PROGRAMMED CELL DEATH PROTEIN 1

TARGET->LIGAND

Amount:

Related Record Type Details


					XPV3BT6FPY

Eciskafusp alfa

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL