U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 15:04:56 GMT 2023
Edited
by admin
on Sat Dec 16 15:04:56 GMT 2023
Source Materials Class ORGANISM
Source Materials Type ALLOGENIC HUMAN
Source Materials State LIVE
Source Materials Parent
Development Stage NEWBORN
Part Location CORD
Part UMBILICAL CORD; BLOOD
Fraction Material Type CELLS
Fraction Name NATURAL KILLER
Record UNII
XO25H8E4QP
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Taniraleucel
INN   USAN  
Official Name English
taniraleucel [INN]
Common Name English
PNK-007
Code English
Allogeneic natural killer (NK) cells derived from CD34+ human placental stem/progenitor cells. The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell
Common Name English
ALLOGENEIC UMBILICAL CORD BLOOD-DERIVED, CULTURE-EXPANDED NATURAL KILLER CELLS
Common Name English
TANIRALEUCEL [USAN]
Common Name English
Taniraleucel [WHO-DD]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 809021
Created by admin on Sat Dec 16 15:04:56 GMT 2023 , Edited by admin on Sat Dec 16 15:04:56 GMT 2023
Code System Code Type Description
INN
11279
Created by admin on Sat Dec 16 15:04:56 GMT 2023 , Edited by admin on Sat Dec 16 15:04:56 GMT 2023
PRIMARY
SMS_ID
300000025374
Created by admin on Sat Dec 16 15:04:56 GMT 2023 , Edited by admin on Sat Dec 16 15:04:56 GMT 2023
PRIMARY
NCI_THESAURUS
C173877
Created by admin on Sat Dec 16 15:04:56 GMT 2023 , Edited by admin on Sat Dec 16 15:04:56 GMT 2023
PRIMARY
USAN
LM-03
Created by admin on Sat Dec 16 15:04:56 GMT 2023 , Edited by admin on Sat Dec 16 15:04:56 GMT 2023
PRIMARY
FDA UNII
XO25H8E4QP
Created by admin on Sat Dec 16 15:04:56 GMT 2023 , Edited by admin on Sat Dec 16 15:04:56 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> CONSTITUENT ALWAYS PRESENT
PARENT -> ACTIVE CONSTITUENT ALWAYS PRESENT
PARENT -> CONSTITUENT ALWAYS PRESENT
Related Record Type Details
ACTIVE MOIETY

Agent Modifications

Modification Process Modification Role Modification Type Amount Fragment Name Fragment ID
CULTURE EXPANSION BIOLOGICAL THROMBOPOIETIN 5651J3R2JF
Name Property Type Amount Referenced Substance Defining Parameters References
ANTIGEN NOT EXPRESSED BIOLOGICAL
ANTIGEN EXPRESSED BIOLOGICAL