Taniraleucel

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 03:38:42 GMT 2025` Edited by `admin` on `Wed Apr 02 03:38:42 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	ALLOGENIC HUMAN
Source Materials State	LIVE
Source Materials Parent	`G0T704E6Z3` HOMO SAPIENS WHOLE
Development Stage	NEWBORN
Part Location	CORD
Part	umbilical cord; blood
Fraction Material Type	cells
Fraction Name	natural killer
Record UNII	XO25H8E4QP
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Allogeneic natural killer (NK) cells derived from CD34+ human placental stem/progenitor cells. The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell

Preferred Name

English

Taniraleucel

Official Name

English

taniraleucel [INN]

Common Name

English

PNK-007

Code

English

ALLOGENEIC UMBILICAL CORD BLOOD-DERIVED, CULTURE-EXPANDED NATURAL KILLER CELLS

Common Name

English

TANIRALEUCEL [USAN]

Common Name

English

Taniraleucel [WHO-DD]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

809021

Created by admin on Wed Apr 02 03:38:42 GMT 2025 , Edited by admin on Wed Apr 02 03:38:42 GMT 2025

Code System Code Type Description

INN

11279

Created by admin on Wed Apr 02 03:38:42 GMT 2025 , Edited by admin on Wed Apr 02 03:38:42 GMT 2025

PRIMARY

SMS_ID

300000025374

Created by admin on Wed Apr 02 03:38:42 GMT 2025 , Edited by admin on Wed Apr 02 03:38:42 GMT 2025

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NCI_THESAURUS

C173877

Created by admin on Wed Apr 02 03:38:42 GMT 2025 , Edited by admin on Wed Apr 02 03:38:42 GMT 2025

PRIMARY

USAN

LM-03

Created by admin on Wed Apr 02 03:38:42 GMT 2025 , Edited by admin on Wed Apr 02 03:38:42 GMT 2025

PRIMARY

FDA UNII

XO25H8E4QP

Created by admin on Wed Apr 02 03:38:42 GMT 2025 , Edited by admin on Wed Apr 02 03:38:42 GMT 2025

PRIMARY

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ACTIVE MOIETY

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Agent Modifications

Modification Process	Modification Role	Modification Type	Amount	Fragment Name	Fragment ID
CULTURE	EXPANSION	BIOLOGICAL		THROMBOPOIETIN	5651J3R2JF

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
ANTIGEN NOT EXPRESSED	BIOLOGICAL		`ZLW14X2D30` CD3

ANTIGEN EXPRESSED	BIOLOGICAL		`DI9X6F2RHW` NEURAL CELL ADHESION MOLECULE 1