CAMONAGREL

Details

Stereochemistry	RACEMIC
Molecular Formula	C15H16N2O3
Molecular Weight	272.2991
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)C1CCC2=C1C=CC(OCCN3C=CN=C3)=C2

InChI

InChIKey=IRWWXLHSNMVHNY-UHFFFAOYSA-N

InChI=1S/C15H16N2O3/c18-15(19)14-3-1-11-9-12(2-4-13(11)14)20-8-7-17-6-5-16-10-17/h2,4-6,9-10,14H,1,3,7-8H2,(H,18,19)

HIDE SMILES / InChI

Molecular Formula	C15H16N2O3
Molecular Weight	272.2991
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/12886030 | https://www.ncbi.nlm.nih.gov/pubmed/9725489 | https://www.ncbi.nlm.nih.gov/pubmed/9683018

Camonagrel is a novel selective thromboxane synthetase inhibitor patented by Ferrer Internacional S. A. Camonagrel reduced platelet-subendothelium interaction under flow conditions, showing this effect in a range of concentrations lower than in inhibition of platelet aggregation.

Originator

Approval Year

PubMed

Title	Date	PubMed
UK-37, 248, a novel, selective thromboxane synthetase inhibitor with platelet anti-aggregatory and anti-thrombotic activity.	1981 Jul 1-15	6795753
The mechanism of anti-thrombotic, thrombolytic and fibrinolytic actions of camonagrel--a new thromboxane synthase inhibitor.	1995	7778318

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 15:48:30 GMT 2023` Edited by `admin` on `Sat Dec 16 15:48:30 GMT 2023`
Record UNII	XM930M133O
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CAMONAGREL

Official Name

English

(±)-5-(2-IMIDAZOL-1-YLETHOXY)-1-INDANCARBOXYLIC ACID

Systematic Name

English

camonagrel [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1327