U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 09:57:48 GMT 2025
Edited
by admin
on Wed Apr 02 09:57:48 GMT 2025
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
XLR461MD3M
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MM-005
Preferred Name English
ISTIRATUMAB
INN   USAN  
Official Name English
ISTIRATUMAB [USAN]
Common Name English
MM-141
Code English
istiratumab [INN]
Common Name English
Istiratumab [WHO-DD]
Common Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN INSULIN-LIKE GROWTH FACTOR I RECEPTOR/NEUREGULIN RECEPTOR HER3) (HUMAN MONOCLONAL MM-005 HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL MM-005 LIGHT CHAIN, DIMER
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 450314
Created by admin on Wed Apr 02 09:57:48 GMT 2025 , Edited by admin on Wed Apr 02 09:57:48 GMT 2025
Code System Code Type Description
SMS_ID
100000175014
Created by admin on Wed Apr 02 09:57:48 GMT 2025 , Edited by admin on Wed Apr 02 09:57:48 GMT 2025
PRIMARY
CAS
1509928-04-4
Created by admin on Wed Apr 02 09:57:48 GMT 2025 , Edited by admin on Wed Apr 02 09:57:48 GMT 2025
PRIMARY
WIKIPEDIA
Istiratumab
Created by admin on Wed Apr 02 09:57:48 GMT 2025 , Edited by admin on Wed Apr 02 09:57:48 GMT 2025
PRIMARY
FDA UNII
XLR461MD3M
Created by admin on Wed Apr 02 09:57:48 GMT 2025 , Edited by admin on Wed Apr 02 09:57:48 GMT 2025
PRIMARY
USAN
CD-106
Created by admin on Wed Apr 02 09:57:48 GMT 2025 , Edited by admin on Wed Apr 02 09:57:48 GMT 2025
PRIMARY
DRUG BANK
DB15363
Created by admin on Wed Apr 02 09:57:48 GMT 2025 , Edited by admin on Wed Apr 02 09:57:48 GMT 2025
PRIMARY
NCI_THESAURUS
C103863
Created by admin on Wed Apr 02 09:57:48 GMT 2025 , Edited by admin on Wed Apr 02 09:57:48 GMT 2025
PRIMARY
INN
10431
Created by admin on Wed Apr 02 09:57:48 GMT 2025 , Edited by admin on Wed Apr 02 09:57:48 GMT 2025
PRIMARY
From To
1_234 2_234
1_231 2_231
2_225 4_214
1_225 3_214
4_134 4_194
4_23 4_88
3_134 3_194
3_23 3_88
2_633 2_698
2_488 2_562
2_372 2_430
2_266 2_326
2_149 2_205
2_22 2_96
1_633 1_698
1_488 1_562
1_372 1_430
1_266 1_326
1_149 1_205
1_22 1_96
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_302
N 2_302
Related Record Type Details
RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3
TARGET -> INHIBITOR
BINDING
INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR
TARGET -> INHIBITOR
BINDING
Related Record Type Details
ISTIRATUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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