TRIFEZOLAC

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H18N2O2
Molecular Weight	354.4012
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TRIFEZOLAC

Structure Search

SMILES

OC(=O)CC1=C(N(N=C1C2=CC=CC=C2)C3=CC=CC=C3)C4=CC=CC=C4

InChI

InChIKey=YBPNJBYPFNTZIW-UHFFFAOYSA-N

InChI=1S/C23H18N2O2/c26-21(27)16-20-22(17-10-4-1-5-11-17)24-25(19-14-8-3-9-15-19)23(20)18-12-6-2-7-13-18/h1-15H,16H2,(H,26,27)

HIDE SMILES / InChI

Molecular Formula	C23H18N2O2
Molecular Weight	354.4012
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://apps.who.int/iris/bitstream/handle/10665/275695/WHO-EMP-RHT-TSN-2018.1-eng.pdf | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 1253, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | Negwer, M. (1987) Organic-chemical Drugs and Their Synonyms, page 1204, retrieved from: https://books.google.ru/books?id=k6fwAAAAMAAJ

Trifezolac is an ibufenac derivative. It is an analgesic, antipyretic, anti-inflammatory agent.

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
inflammatory response 47 Target ID: GO:0006954 Sources: https://books.google.ru/books?id=0vXTBwAAQBAJ&pg=PA1253&lpg=PA1253&dq=TRIFEZOLAC retrieved from Dictionary of Drugs: Chemical Data, Structures and Bibliographies J. Elks, p.1253	Inhibitor 8297

Patents

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:57:21 GMT 2023` Edited by `admin` on `Fri Dec 15 15:57:21 GMT 2023`
Record UNII	XJ3W180C22
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TRIFEZOLAC

Official Name

English

trifezolac [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257

Created by admin on Fri Dec 15 15:57:21 GMT 2023 , Edited by admin on Fri Dec 15 15:57:21 GMT 2023

Code System Code Type Description

SMS_ID

100000077722

Created by admin on Fri Dec 15 15:57:21 GMT 2023 , Edited by admin on Fri Dec 15 15:57:21 GMT 2023

PRIMARY

EVMPD

SUB11283MIG

Created by admin on Fri Dec 15 15:57:21 GMT 2023 , Edited by admin on Fri Dec 15 15:57:21 GMT 2023

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INN

3830

Created by admin on Fri Dec 15 15:57:21 GMT 2023 , Edited by admin on Fri Dec 15 15:57:21 GMT 2023

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PUBCHEM

3084566

Created by admin on Fri Dec 15 15:57:21 GMT 2023 , Edited by admin on Fri Dec 15 15:57:21 GMT 2023

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CAS

32710-91-1

Created by admin on Fri Dec 15 15:57:21 GMT 2023 , Edited by admin on Fri Dec 15 15:57:21 GMT 2023

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ChEMBL

CHEMBL2106501

Created by admin on Fri Dec 15 15:57:21 GMT 2023 , Edited by admin on Fri Dec 15 15:57:21 GMT 2023

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FDA UNII

XJ3W180C22

Created by admin on Fri Dec 15 15:57:21 GMT 2023 , Edited by admin on Fri Dec 15 15:57:21 GMT 2023

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NCI_THESAURUS

C76824

Created by admin on Fri Dec 15 15:57:21 GMT 2023 , Edited by admin on Fri Dec 15 15:57:21 GMT 2023

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EPA CompTox

DTXSID80186391

Created by admin on Fri Dec 15 15:57:21 GMT 2023 , Edited by admin on Fri Dec 15 15:57:21 GMT 2023

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					XJ3W180C22

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