U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 22:58:05 UTC 2021
Edited
by admin
on Sat Jun 26 22:58:05 UTC 2021
Protein Type MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
XCR2BZ80N7
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TRASTUZUMAB DUOCARMAZINE
INN   WHO-DD  
INN   USAN  
Official Name English
TRASTUZUMAB DUOCARMAZINE [USAN]
Common Name English
TRASTUZUMAB DUOCARMAZINE [INN]
Common Name English
TRASTUZUMAB DUOCARMAZINE [WHO-DD]
Common Name English
SYD-985
Code English
SYD985
Code English
IMMUNOGLOBULIN G1, ANTI-(HUMAN NEU (RECEPTOR)) (HUMAN-MUS MUSCULUS MONOCLONAL SYD977 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL SYD977 LIGHT CHAIN, DIMER, THIOETHER WITH N-((2-(2-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)ETHOXY)ETHOXY)CARBO
Systematic Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS ERBB2 (EPIDERMAL GROWTH FACTOR RECEPTOR 2, RECEPTOR TYROSINEPROTEIN KINASE ERBB-2, EGFR2, HER2, HER-2, P185CERBB2, NEU, CD340)), HUMANIZED MONOCLONAL ANTIBODY CONJUGATED TO THE PRO-DRUG SECO-DUOCARMYCINHYDROXYB
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C129823
Created by admin on Sat Jun 26 22:58:06 UTC 2021 , Edited by admin on Sat Jun 26 22:58:06 UTC 2021
NCI_THESAURUS C1512
Created by admin on Sat Jun 26 22:58:06 UTC 2021 , Edited by admin on Sat Jun 26 22:58:06 UTC 2021
Code System Code Type Description
INN
10273
Created by admin on Sat Jun 26 22:58:06 UTC 2021 , Edited by admin on Sat Jun 26 22:58:06 UTC 2021
PRIMARY
NCI_THESAURUS
C118674
Created by admin on Sat Jun 26 22:58:06 UTC 2021 , Edited by admin on Sat Jun 26 22:58:06 UTC 2021
PRIMARY
FDA UNII
XCR2BZ80N7
Created by admin on Sat Jun 26 22:58:06 UTC 2021 , Edited by admin on Sat Jun 26 22:58:06 UTC 2021
PRIMARY
CAS
1642152-40-6
Created by admin on Sat Jun 26 22:58:06 UTC 2021 , Edited by admin on Sat Jun 26 22:58:06 UTC 2021
PRIMARY
From To
1_22 1_96
1_147 1_203
1_264 1_324
1_370 1_428
2_22 2_96
2_147 2_203
2_264 2_324
2_370 2_428
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_223 3_214
2_223 4_214
1_229 2_229
1_232 2_232
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_300
N 2_300
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL