ADRENOMEDULLIN PEGOL

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 08:17:33 GMT 2025` Edited by `admin` on `Wed Apr 02 08:17:33 GMT 2025`
Protein Type	HORMONE
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	XCF7HHB5HQ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ADRENOMEDULLIN PEGOL

Official Name

English

HUMAN ADRENOMEDULLIN, C-TERMINAL L-TYROSIL AMIDE, PEGYLATED (PEG-40000)AT O4 OF Y1 WITH ((3S)-3-AMINO-4-(((2R)-1-AMINO-3-(((3RS)-2,5-DIOXO-1-(3-OXO-3-(.ALPHA.-METHYL(POLYOXYETHYLENE)-.OMEGA.-AMINO)PROPYL)PYRROLIDIN-3-YL)SULFANYL)-1-OXOPROPAN-2-YL)AMINO)-

Preferred Name

English

POLY(OXY-1,2-ETHANEDIYL), .ALPHA.-METHYL-.OMEGA.-HYDROXY-, 1-ETHER WITH ADRENOMEDULLIN (1-(O-((((3S)-3-AMINO-4-(((1R)-2-AMINO-1-(((1-(3-((2-HYDROXYETHYL)AMINO)-3-OXOPROPYL)-2,5-DIOXO-3-PYRROLIDINYL)THIO)METHYL)-2-OXOETHYL)AMINO)-4-OXOBUTYL)AMINO)CARBONYL

Common Name

English

adrenomedullin pegol [INN]

Common Name

English

Code System Code Type Description

INN

11409

Created by admin on Wed Apr 02 08:17:33 GMT 2025 , Edited by admin on Wed Apr 02 08:17:33 GMT 2025

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FDA UNII

XCF7HHB5HQ

Created by admin on Wed Apr 02 08:17:33 GMT 2025 , Edited by admin on Wed Apr 02 08:17:33 GMT 2025

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CAS

1432735-93-7

Created by admin on Wed Apr 02 08:17:33 GMT 2025 , Edited by admin on Wed Apr 02 08:17:33 GMT 2025

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NCI_THESAURUS

C175737

Created by admin on Wed Apr 02 08:17:33 GMT 2025 , Edited by admin on Wed Apr 02 08:17:33 GMT 2025

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SMS_ID

100000178340

Created by admin on Wed Apr 02 08:17:33 GMT 2025 , Edited by admin on Wed Apr 02 08:17:33 GMT 2025

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From	To
1_16	1_21

Related Record Type Details


					QA0A21Y20D

METABOLITE ACTIVE -> PRODRUG

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1]	N-TERMINUS			TYROSINE PEG-900 (ADRENOMEDULLIN PEGOL MODIFICATION)	P8FWH4MP8C
AMINO_ACID_SUBSTITUTION	[1_52]	C-TERMINUS			TYROSINAMIDE, L-	05LU01CS4T

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL

Molecular Formula	CHEMICAL