VORSETUZUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 21:34:49 GMT 2025` Edited by `admin` on `Mon Mar 31 21:34:49 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	XC95WX725U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

VORSETUZUMAB

Official Name

English

H-1F6

Preferred Name

English

Immunoglobulin G1, anti-(human/Macaca fascicularis CD70 antigen) (human-Mus musculus monoclonal BR108 ?1-chain), disulfide with human-Mus musculus monoclonal BR108 ?-chain, dimer

Common Name

English

Vorsetuzumab [WHO-DD]

Common Name

English

balertatug

Common Name

English

VORSETUZUMAB [USAN]

Common Name

English

SGN-70

Code

English

balertatug [INN]

Common Name

English

H1F6

Code

English

vorsetuzumab [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C129823

Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025

Code System Code Type Description

SMS_ID

300000021937

Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025

PRIMARY

NCI_THESAURUS

C152916

Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025

PRIMARY

FDA UNII

XC95WX725U

Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025

PRIMARY

USAN

YY-56

Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025

PRIMARY

ChEMBL

CHEMBL2108673

Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025

PRIMARY

INN

9611

Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025

PRIMARY

CAS

1165740-62-4

Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025

ALTERNATIVE

CAS

3010940-29-8

Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025

PRIMARY

From	To
1_22	1_96
1_145	1_201
1_262	1_322
1_368	1_426
2_22	2_96
2_145	2_201
2_262	2_322
2_368	2_426
3_23	3_92
3_138	3_198
4_23	4_92
4_138	4_198
1_221	3_218
2_221	4_218
1_227	2_227
1_230	2_230

Glycosylation Link Type	Site
N	1_298
N	2_298

Related Record Type Details


					Q5W41WNI30

TARGET -> INHIBITOR

Amount:


					699619YVTQ

VORSETUZUMAB MAFODOTIN

CONJUGATE -> PARENT

Amount:

Related Record Type Details


					XC95WX725U

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS		Amount:	PIDOLIC ACID	SZB83O1W42
AMINO ACID REMOVAL	[1_448] [2_448]	C-TERMINUS		Amount:	LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL