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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Mon Mar 31 21:34:49 GMT 2025
Edited
by admin
on Mon Mar 31 21:34:49 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
XC95WX725U
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VORSETUZUMAB
INN   USAN   WHO-DD  
USAN   INN  
Official Name English
H-1F6
Preferred Name English
Immunoglobulin G1, anti-(human/Macaca fascicularis CD70 antigen) (human-Mus musculus monoclonal BR108 ?1-chain), disulfide with human-Mus musculus monoclonal BR108 ?-chain, dimer
Common Name English
Vorsetuzumab [WHO-DD]
Common Name English
balertatug
Common Name English
VORSETUZUMAB [USAN]
Common Name English
SGN-70
Code English
balertatug [INN]
Common Name English
H1F6
Code English
vorsetuzumab [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C129823
Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025
Code System Code Type Description
SMS_ID
300000021937
Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025
PRIMARY
NCI_THESAURUS
C152916
Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025
PRIMARY
FDA UNII
XC95WX725U
Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025
PRIMARY
USAN
YY-56
Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025
PRIMARY
ChEMBL
CHEMBL2108673
Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025
PRIMARY
INN
9611
Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025
PRIMARY
CAS
1165740-62-4
Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025
ALTERNATIVE
CAS
3010940-29-8
Created by admin on Mon Mar 31 21:34:49 GMT 2025 , Edited by admin on Mon Mar 31 21:34:49 GMT 2025
PRIMARY
From To
1_22 1_96
1_145 1_201
1_262 1_322
1_368 1_426
2_22 2_96
2_145 2_201
2_262 2_322
2_368 2_426
3_23 3_92
3_138 3_198
4_23 4_92
4_138 4_198
1_221 3_218
2_221 4_218
1_227 2_227
1_230 2_230
Glycosylation Link Type Site
N 1_298
N 2_298
Related Record Type Details
CD27 LIGAND
TARGET -> INHIBITOR
VORSETUZUMAB MAFODOTIN
CONJUGATE -> PARENT
Related Record Type Details
VORSETUZUMAB
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO_ACID_SUBSTITUTION [1_1] [2_1] N-TERMINUS Amount: PIDOLIC ACID SZB83O1W42
AMINO ACID REMOVAL [1_448] [2_448] C-TERMINUS Amount: LYSINE K3Z4F929H6
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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