BISMUTH SODIUM TRIGLYCOLLAMATE

US Previously Marketed

First approved in 1946

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H7BiNO7.3C6H7NO6.7Na
Molecular Weight	1142.3997
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of BISMUTH SODIUM TRIGLYCOLLAMATE

Structure Search

SMILES

[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[H][N+](CC([O-])=O)(CC([O-])=O)CC([O-])=O.[H][N+](CC([O-])=O)(CC([O-])=O)CC([O-])=O.[H][N+](CC([O-])=O)(CC([O-])=O)CC([O-])=O.[O-]C(=O)C[NH+](CC([O-])=O)CC(=O)O[Bi]=O

InChI

InChIKey=HCMDBCQMTCRYHB-UHFFFAOYSA-F

InChI=1S/4C6H9NO6.Bi.7Na.O/c4*8-4(9)1-7(2-5(10)11)3-6(12)13;;;;;;;;;/h4*1-3H2,(H,8,9)(H,10,11)(H,12,13);;;;;;;;;/q;;;;8*+1;/p-8

HIDE SMILES / InChI

Molecular Formula	C6H7NO6
Molecular Weight	189.1229
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C6H7BiNO7
Molecular Weight	414.1027
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.drugfuture.com/chemdata/bismuth-sodium-triglycollamate.html | https://www.ncbi.nlm.nih.gov/pubmed/20269094

BISMUTH SODIUM TRIGLYCOLLAMATE, a bismuth compound, is a lupus erythematosus suppressant.

Approval Year

PubMed

Title	Date	PubMed
Disseminated lupus erythematosus treated with sodium bismuth triglycollamate (bistrimate tablets).	1947 Jun	20247767
Bistrimate (sodium bismuth triglycollamate) administered by mouth in the treatment of chronic discoid lupus erythematosus preliminary report.	1947 Sep	20269094
Inefficacy of sodium bismuth triglycollamate in the treatment of warts.	1958 Jul	13560716
Treatment of resistant verruca vulgaris with bismuth sodium triglycollamate.	1962 Aug	15445818
Chronic resistant otitis media treated with oral bismuth sodium triglycollamate.	1962 Jul	13869557

Sample Use Guides

In Vivo Use Guide

1-2 tablets (75-150 mg of metallic bismuth) three times daily for as long as 26 week.

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:07:40 GMT 2023` Edited by `admin` on `Fri Dec 15 15:07:40 GMT 2023`
Record UNII	X9A8P4D3IF
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BISMUTH SODIUM TRIGLYCOLLAMATE

Common Name

English

BISMUTH SODIUM TRIGLYCOLLAMATE [MI]

Common Name

English

Code System Code Type Description

EVMPD

SUB33748