U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Tue Apr 01 21:40:11 GMT 2025
Edited
by admin
on Tue Apr 01 21:40:11 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
X8JR0I7JE1
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
talacotuzumab [INN]
Preferred Name English
TALACOTUZUMAB
INN  
Official Name English
CSL-362
Code English
IMMUNOGLOBULIN G1-2-KAPPA, ANTI-(HOMO SAPIENS IL3RA (INTERLEUKIN 3 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN 3 RECEPTOR ALPHA (LOW AFFINITY), CD123)), HUMANIZED MONOCLONAL ANTIBODYGAMMA1-2 HEAVY CHAIN (1-450) (HUMANIZED VH (HOMO SAPIENS IGHV5-51*01 (82.70%) -(
Common Name English
ANTI-IL-3 RECEPTOR ALPHA MONOCLONAL ANTIBODY CSL362
Common Name English
Talacotuzumab [WHO-DD]
Common Name English
JNJ-56022473
Code English
CSL362
Code English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Tue Apr 01 21:40:12 GMT 2025 , Edited by admin on Tue Apr 01 21:40:12 GMT 2025
FDA ORPHAN DRUG 478715
Created by admin on Tue Apr 01 21:40:12 GMT 2025 , Edited by admin on Tue Apr 01 21:40:12 GMT 2025
NCI_THESAURUS C129822
Created by admin on Tue Apr 01 21:40:12 GMT 2025 , Edited by admin on Tue Apr 01 21:40:12 GMT 2025
Code System Code Type Description
CAS
1826831-79-1
Created by admin on Tue Apr 01 21:40:12 GMT 2025 , Edited by admin on Tue Apr 01 21:40:12 GMT 2025
PRIMARY
NCI_THESAURUS
C102784
Created by admin on Tue Apr 01 21:40:12 GMT 2025 , Edited by admin on Tue Apr 01 21:40:12 GMT 2025
PRIMARY
INN
10508
Created by admin on Tue Apr 01 21:40:12 GMT 2025 , Edited by admin on Tue Apr 01 21:40:12 GMT 2025
PRIMARY
FDA UNII
X8JR0I7JE1
Created by admin on Tue Apr 01 21:40:12 GMT 2025 , Edited by admin on Tue Apr 01 21:40:12 GMT 2025
PRIMARY
SMS_ID
100000177798
Created by admin on Tue Apr 01 21:40:12 GMT 2025 , Edited by admin on Tue Apr 01 21:40:12 GMT 2025
PRIMARY
DRUG BANK
DB14796
Created by admin on Tue Apr 01 21:40:12 GMT 2025 , Edited by admin on Tue Apr 01 21:40:12 GMT 2025
PRIMARY
From To
1_22 1_96
1_147 1_203
1_264 1_324
1_370 1_428
2_22 2_96
2_147 2_203
2_264 2_324
2_370 2_428
1_223 3_220
1_229 2_229
1_232 2_232
2_223 4_220
3_23 3_94
3_140 3_200
4_23 4_94
4_140 4_200
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_300
N 2_300
Related Record Type Details
INTERLEUKIN-3 RECEPTOR SUBUNIT ALPHA
TARGET -> INHIBITOR
Related Record Type Details
TALACOTUZUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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