Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C21H21O4P |
| Molecular Weight | 368.3628 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC=CC=C1OP(=O)(OC2=CC=CC=C2C)OC3=CC=CC=C3C
InChI
InChIKey=YSMRWXYRXBRSND-UHFFFAOYSA-N
InChI=1S/C21H21O4P/c1-16-10-4-7-13-19(16)23-26(22,24-20-14-8-5-11-17(20)2)25-21-15-9-6-12-18(21)3/h4-15H,1-3H3
| Molecular Formula | C21H21O4P |
| Molecular Weight | 368.3628 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Impairment of glutamate signaling in mouse central nervous system neurons in vitro by tri-ortho-cresyl phosphate at noncytotoxic concentrations. | 2014-11 |
|
| Induction of autophagy by TOCP in differentiated human neuroblastoma cells lead to degradation of cytoskeletal components and inhibition of neurite outgrowth. | 2013-08-09 |
|
| Identifying safer anti-wear triaryl phosphate additives for jet engine lubricants. | 2013-03-25 |
|
| Biochemical, histopathological and clinical evaluation of delayed effects caused by methamidophos isoforms and TOCP in hens: ameliorative effects using control of calcium homeostasis. | 2012-12-08 |
|
| Involvement of neuropathy target esterase in tri-ortho-cresyl phosphate-induced testicular spermatogenesis failure and growth inhibition of spermatogonial stem cells in mice. | 2012-05-20 |
|
| Changes in beclin-1 and micro-calpain expression in tri-ortho-cresyl phosphate-induced delayed neuropathy. | 2012-05-05 |
|
| Acute airway irritation of methyl formate in mice. | 2012-02 |
|
| Induction of plasma acetylcholinesterase activity in mice challenged with organophosphorus poisons. | 2011-09-01 |
|
| Exposure to airborne organophosphates originating from hydraulic and turbine oils among aviation technicians and loaders. | 2010-12 |
|
| Vacuoles in dorsal root Ganglia neurons: some questions. | 2010-10 |
|
| Development of diagnostics in the search for an explanation of aerotoxic syndrome. | 2010-09-01 |
|
| Neuropathological studies of chickens following exposure to chlorpyrifos. | 2010-07 |
|
| Vacuolation of sensory ganglion neuron cytoplasm in rats with long-term exposure to organophosphates. | 2010-06 |
|
| [Effect of phenylmethylsulfonyl fluoride pretreated on neurofilament subunits in spinal cords of hens administrated with tri-o-cresyl phosphate]. | 2010-04 |
|
| Adulterated cocaine and lessons learned from the Jake walk blues. | 2010-03 |
|
| House dust concentrations of organophosphate flame retardants in relation to hormone levels and semen quality parameters. | 2010-03 |
|
| Toxic neuropathies. | 2010-02-09 |
|
| Organophosphorus-induced delayed neuropathy: a simple and efficient therapeutic strategy. | 2010-02-01 |
|
| Identification and characterization of biomarkers of organophosphorus exposures in humans. | 2010 |
|
| Thirteen-year follow-up of patients with tri-ortho-cresyl phosphate poisoning in northern suburbs of Xi'an in China. | 2009-11 |
|
| Allergic contact dermatitis from tricresyl phosphate. | 2009-10-08 |
|
| Phenylmethylsulfonyl fluoride protects against the degradation of neurofilaments in tri-ortho-cresyl phosphate (TOCP) induced delayed neuropathy. | 2009-08-21 |
|
| Effect of inhibition of neuropathy target esterase in mouse nervous tissues in vitro on phosphatidylcholine and lysophosphatidylcholine homeostasis. | 2009-07-22 |
|
| The homeostasis of phosphatidylcholine and lysophosphatidylcholine in nervous tissues of mice was not disrupted after administration of tri-o-cresyl phosphate. | 2009-06 |
|
| Amplify, amplify: shotgun proteomics boosts the signal for biomarker discovery. | 2009-05 |
|
| Neurofilaments degradation as an early molecular event in tri-ortho-cresyl phosphate (TOCP) induced delayed neuropathy. | 2009-04-28 |
|
| Radial neuropathy due to occupational lead exposure: Phenotypic and electrophysiological characteristics of five patients. | 2009-04 |
|
| Respiratory and dermal exposure to organophosphorus flame retardants and tetrabromobisphenol A at five work environments. | 2009-02-01 |
|
| Design of a small personal air monitor and its application in aircraft. | 2009-01-15 |
|
| The homeostasis of phosphatidylcholine and lysophosphatidylcholine was not disrupted during tri-o-cresyl phosphate-induced delayed neurotoxicity in hens. | 2008-10-30 |
|
| Worms and germs, drink and dementia: US health, society, and policy in the early 20th century. | 2008-10 |
|
| Growth inhibition and induction of G(1) phase cell cycle arrest in neuroblastoma SH-SY5Y cell by tri-ortho-cresyl phosphate. | 2008-09 |
|
| Determination of ortho-cresyl phosphate isomers of tricresyl phosphate used in aircraft turbine engine oils by gas chromatography and mass spectrometry. | 2008-07-25 |
|
| Shear small-angle light scattering studies of shear-induced concentration fluctuations and steady state viscoelastic properties. | 2008-04-28 |
|
| Effects of calcium gluconate and PMSF in the treatment of acute intoxication of chicken by TOCP. | 2008-03 |
|
| An Effective On-line Polymer Characterization Technique by Using SALS Image Processing Software and Wavelet Analysis. | 2008 |
|
| Axonal degeneration and neuropathy target esterase. | 2007-09 |
|
| Antibodies to neural proteins in organophosphorus-induced delayed neuropathy (OPIDN) and its amelioration. | 2007-08-23 |
|
| Verapamil abolished the enhancement of protein phosphorylation of brainstem mitochondria and synaptosomes from the hens dosed with tri-o-cresyl phosphate. | 2007-07 |
|
| [Determination of three organophosphorous flame retardants in textiles by gas chromatography]. | 2007-05 |
|
| The contribution of oxidation and deacetylation to acetaminophen nephrotoxicity in female Sprague-Dawley rats. | 1997-09-19 |
|
| Comparison of the relative inhibition of acetylcholinesterase and neuropathy target esterase in rats and hens given cholinesterase inhibitors. | 1995-01 |
|
| Histopathological assessment of triphenyl phosphite neurotoxicity in the hen. | 1988 |
|
| Dose-related beneficial and adverse effects of dietary corticosterone on organophosphorus-induced delayed neuropathy in chickens. | 1986-04 |
|
| Lymphocyte and brain neurotoxic esterase: dose and time dependence of inhibition in the hen examined with three organophosphorus esters. | 1986-03-30 |
|
| Assessment of the delayed neurotoxic potential of isopropyl triphenylphosphate using a nontraditional testing strategy. | 1984 |
|
| The time course of protection from delayed neurotoxicity induced by tri-o-cresyl phosphate and O,O-diisopropyl phosphorofluoridate by phenyl methyl sulfonyl fluoride in chickens. | 1983-09 |
|
| Jamaica ginger paralysis. Forty-seven-year follow-up. | 1978-08 |
|
| [Prevention of experimental neuritis induced by nitrofurantoin and triorthocresylphosphate]. | 1977-02 |
|
| The Jake Walk Blues. A toxicologic tragedy mirrored in American popular music. | 1976-12 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:53:18 GMT 2025
by
admin
on
Mon Mar 31 19:53:18 GMT 2025
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| Record UNII |
X8II18JD0A
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| Record Status |
Validated (UNII)
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| Record Version |
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201-103-5
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DTXSID6032192
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Tri-o-cresyl phosphate
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m11211
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6527
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4084
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X8II18JD0A
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78-30-8
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438
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300000053630
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