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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 02:55:39 GMT 2025
Edited
by admin
on Wed Apr 02 02:55:39 GMT 2025
Protein Type PROBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
X7F47LV4T7
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ANTI-CD166 PROBODY-DRUG
Preferred Name English
PRALUZATAMAB
USAN   INN  
Official Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE) (HUMAN MONOCLONAL CX-191 .GAMMA.1-CHAIN), DISULFIDE WITH PRODOMAIN PROTEIN (SYNTHETIC MASKING MOIETY AND CLEAVABLE MOIETY PROTEASE SUBSTRATE-CONTAINING) FUSION PROTEIN WITH HUMAN
Common Name English
PRALUZATAMAB [USAN]
Common Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS CD166 (ACTIVATED LEUCOCYTE CELL ADHESION MOLECULE, ALCAM)), HUMANIZED MONOCLONAL ANTIBODY
Common Name English
CX-191
Common Name English
praluzatamab [INN]
Common Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS CD166 ANTIGEN (ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE)); HUMANIZED MONOCLONAL ANTIBODY; .GAMMA.1 HEAVY CHAIN HUMANIZED (1-450) (VH (HOMO SAPIENS IGHV2-5*01 (89%) (IGHD)-IGHJ4*01 (93%)) (10.7.13) (1-121)-HOM
Common Name English
Code System Code Type Description
INN
10940
Created by admin on Wed Apr 02 02:55:39 GMT 2025 , Edited by admin on Wed Apr 02 02:55:39 GMT 2025
PRIMARY
CAS
2145109-70-0
Created by admin on Wed Apr 02 02:55:39 GMT 2025 , Edited by admin on Wed Apr 02 02:55:39 GMT 2025
PRIMARY
USAN
HI-168
Created by admin on Wed Apr 02 02:55:39 GMT 2025 , Edited by admin on Wed Apr 02 02:55:39 GMT 2025
PRIMARY
SMS_ID
300000010807
Created by admin on Wed Apr 02 02:55:39 GMT 2025 , Edited by admin on Wed Apr 02 02:55:39 GMT 2025
PRIMARY
FDA UNII
X7F47LV4T7
Created by admin on Wed Apr 02 02:55:39 GMT 2025 , Edited by admin on Wed Apr 02 02:55:39 GMT 2025
PRIMARY
NCI_THESAURUS
C174944
Created by admin on Wed Apr 02 02:55:39 GMT 2025 , Edited by admin on Wed Apr 02 02:55:39 GMT 2025
PRIMARY
From To
1_22 1_97
1_148 1_204
1_224 3_270
1_230 2_230
1_233 2_233
1_265 1_325
1_371 1_429
2_22 2_97
2_148 2_204
2_224 4_270
2_265 2_325
2_371 2_429
3_9 3_20
3_74 3_144
4_9 4_20
4_74 4_144
3_190 3_250
4_190 4_250
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_301
N 2_301
Related Record Type Details
MATRIX METALLOPROTEINASE-14
METABOLIC ENZYME -> SUBSTRATE

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO_ACID_SUBSTITUTION [1_1] [2_1] [3_1] [4_1] N-TERMINUS PIDOLIC ACID SZB83O1W42
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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