E-2078

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C50H81N15O9
Molecular Weight	1036.2732
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCNC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)[C@H](CC2=CC=C(O)C=C2)NC

InChI

InChIKey=JENWDDCMEATQSR-ONSKYXJOSA-N

InChI=1S/C50H81N15O9/c1-8-56-44(70)37(24-30(2)3)64-47(73)40(17-13-23-58-50(53)54)65(7)48(74)35(16-12-22-57-49(51)52)62-45(71)38(25-31(4)5)63-46(72)39(27-32-14-10-9-11-15-32)61-42(68)29-59-41(67)28-60-43(69)36(55-6)26-33-18-20-34(66)21-19-33/h9-11,14-15,18-21,30-31,35-40,55,66H,8,12-13,16-17,22-29H2,1-7H3,(H,56,70)(H,59,67)(H,60,69)(H,61,68)(H,62,71)(H,63,72)(H,64,73)(H4,51,52,57)(H4,53,54,58)/t35-,36-,37+,38-,39-,40-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C50H81N15O9
Molecular Weight	1036.2732
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
[Effects of the dynorphin derivative "E2078" on hemodynamics and plasma catecholamines in dogs].	1990 Jul	1976830
Cloning and pharmacological characterization of a rat kappa opioid receptor.	1993 Nov 1	8234341
Opioid efficacy in a C6 glioma cell line stably expressing the human kappa opioid receptor.	1999 Feb	9918595

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:39:50 GMT 2023` Edited by `admin` on `Fri Dec 15 19:39:50 GMT 2023`
Record UNII	X741EI11EL
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

E-2078

Common Name

English

1-8-DYNORPHIN B (SWINE), N-METHYL-7-(N2-METHYL-L-ARGININE)-8-(N-ETHYL-D-LEUCINAMIDE)-

Systematic Name

English

66A078

Code

English

Code System Code Type Description

CAS

103613-84-9

Created by admin on Fri Dec 15 19:39:50 GMT 2023 , Edited by admin on Fri Dec 15 19:39:50 GMT 2023

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FDA UNII

X741EI11EL

Created by admin on Fri Dec 15 19:39:50 GMT 2023 , Edited by admin on Fri Dec 15 19:39:50 GMT 2023

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EPA CompTox

DTXSID40145949

Created by admin on Fri Dec 15 19:39:50 GMT 2023 , Edited by admin on Fri Dec 15 19:39:50 GMT 2023

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PUBCHEM

122220

Created by admin on Fri Dec 15 19:39:50 GMT 2023 , Edited by admin on Fri Dec 15 19:39:50 GMT 2023

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