VALOFANE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	UNKNOWN
Molecular Formula	C10H14N2O4
Molecular Weight	226.2292
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of VALOFANE

Structure Search

SMILES

CC1CC(CC=C)(C(=O)NC(N)=O)C(=O)O1

InChI

InChIKey=LVJAHKSVOQLCEV-UHFFFAOYSA-N

InChI=1S/C10H14N2O4/c1-3-4-10(7(13)12-9(11)15)5-6(2)16-8(10)14/h3,6H,1,4-5H2,2H3,(H3,11,12,13,15)

HIDE SMILES / InChI

Molecular Formula	C10H14N2O4
Molecular Weight	226.2292
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6118275 | https://books.google.ru/books?id=xUlaDwAAQBAJ&pg=PT1635&lpg=PT1635&dq=VALOFANE retrieved from Drugs: Synonyms and Properties: Synonyms and Properties edited by George W.A Milne

Valofane is an atypical barbiturate. It is a tautomer (and prodrug) of proxibarbal Valofane is a neurotropic drug. It has sedative and hypnotic action.

CNS Activity

Approval Year

PubMed

PubMed

Title	Date	PubMed
Pharmacokinetics of 14C-2-allophanyl-2-allyl -gamma-valero-lactone: a prodrug of proxibarbal in rats.	1981	6118275

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:48:36 GMT 2023` Edited by `admin` on `Fri Dec 15 15:48:36 GMT 2023`
Record UNII	X71N6E5IPO
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

VALOFANE

Official Name

English

valofane [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29756

Created by admin on Fri Dec 15 15:48:36 GMT 2023 , Edited by admin on Fri Dec 15 15:48:36 GMT 2023

Code System Code Type Description

ChEMBL

CHEMBL2104479

Created by admin on Fri Dec 15 15:48:36 GMT 2023 , Edited by admin on Fri Dec 15 15:48:36 GMT 2023

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SMS_ID

100000079067

Created by admin on Fri Dec 15 15:48:36 GMT 2023 , Edited by admin on Fri Dec 15 15:48:36 GMT 2023

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INN

4055

Created by admin on Fri Dec 15 15:48:36 GMT 2023 , Edited by admin on Fri Dec 15 15:48:36 GMT 2023

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EPA CompTox

DTXSID20863139

Created by admin on Fri Dec 15 15:48:36 GMT 2023 , Edited by admin on Fri Dec 15 15:48:36 GMT 2023

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FDA UNII

X71N6E5IPO

Created by admin on Fri Dec 15 15:48:36 GMT 2023 , Edited by admin on Fri Dec 15 15:48:36 GMT 2023

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CAS

3258-51-3

Created by admin on Fri Dec 15 15:48:36 GMT 2023 , Edited by admin on Fri Dec 15 15:48:36 GMT 2023

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WIKIPEDIA

VALOFANE

Created by admin on Fri Dec 15 15:48:36 GMT 2023 , Edited by admin on Fri Dec 15 15:48:36 GMT 2023

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ECHA (EC/EINECS)

221-857-9

Created by admin on Fri Dec 15 15:48:36 GMT 2023 , Edited by admin on Fri Dec 15 15:48:36 GMT 2023

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MESH

C000192

Created by admin on Fri Dec 15 15:48:36 GMT 2023 , Edited by admin on Fri Dec 15 15:48:36 GMT 2023

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PUBCHEM

71122

Created by admin on Fri Dec 15 15:48:36 GMT 2023 , Edited by admin on Fri Dec 15 15:48:36 GMT 2023

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NCI_THESAURUS

C76952

Created by admin on Fri Dec 15 15:48:36 GMT 2023 , Edited by admin on Fri Dec 15 15:48:36 GMT 2023

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EVMPD

SUB00011MIG

Created by admin on Fri Dec 15 15:48:36 GMT 2023 , Edited by admin on Fri Dec 15 15:48:36 GMT 2023

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Related Record Type Details


					X71N6E5IPO

VALOFANE

ACTIVE MOIETY