N-Hydroxy-osimertinib

Details

Stereochemistry	ACHIRAL
Molecular Formula	C28H33N7O3
Molecular Weight	515.6067
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC(N(C)CCN(C)C)=C(NC(=O)C=C)C=C1N(O)C2=NC(=CC=N2)C3=CN(C)C4=C3C=CC=C4

InChI

InChIKey=ZAMUFLUSAAVGQF-UHFFFAOYSA-N

InChI=1S/C28H33N7O3/c1-7-27(36)30-22-16-25(26(38-6)17-24(22)33(4)15-14-32(2)3)35(37)28-29-13-12-21(31-28)20-18-34(5)23-11-9-8-10-19(20)23/h7-13,16-18,37H,1,14-15H2,2-6H3,(H,30,36)

HIDE SMILES / InChI

Molecular Formula	C28H33N7O3
Molecular Weight	515.6067
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Wed Apr 02 17:38:39 GMT 2025` Edited by `admin` on `Wed Apr 02 17:38:39 GMT 2025`
Record UNII	X436A98JWG
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

N-Hydroxy-osimertinib

Common Name

English

N-Hydroxyl-osimertinib

Preferred Name

English

N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-5-(hydroxy(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-4-methoxyphenyl)acrylamide

Systematic Name

English

Code System Code Type Description

PUBCHEM

169490783

Created by admin on Wed Apr 02 17:38:39 GMT 2025 , Edited by admin on Wed Apr 02 17:38:39 GMT 2025

PRIMARY

FDA UNII

X436A98JWG

Created by admin on Wed Apr 02 17:38:39 GMT 2025 , Edited by admin on Wed Apr 02 17:38:39 GMT 2025

PRIMARY

Related Record Type Details


					3C06JJ0Z2O

OSIMERTINIB

PARENT -> METABOLITE

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC
Volume of Distribution	PHARMACOKINETIC
Tmax	PHARMACOKINETIC