Enzelkitug

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 13:57:31 GMT 2025` Edited by `admin` on `Wed Apr 02 13:57:31 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMANIZED RABBIT
Sequence Type	COMPLETE
Record UNII	X3XW6WQP6G
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

H-gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV3-23*01 (81.6%) -(IGHD) -IGHJ3*02 (91.7%) M123>T (114), CDR-IMGT [8.7.13] (26-33.51-57.96-108)) (1-119) -Homo sapiens IGHG1*03v (100%) G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1 R120>K (216)

Preferred Name

English

Enzelkitug

Official Name

English

enzelkitug [INN]

Common Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens CCR8 (C-C motif chemokine receptor 8, CKR-L1, CDw198) N-terminus], humanized monoclonal antibody

Common Name

English

Immunoglobulin G1, anti-(human CC chemokine receptor CCR8) (human-Oryctolagus cuniculus monoclonal RG6411 ?1-chain), disulfide with human-Oryctolagus cuniculus monoclonal RG6411 ?-chain, dimer

Common Name

English

Code System Code Type Description

FDA UNII

X3XW6WQP6G

Created by admin on Wed Apr 02 13:57:31 GMT 2025 , Edited by admin on Wed Apr 02 13:57:31 GMT 2025

PRIMARY

CAS

2999644-88-9

Created by admin on Wed Apr 02 13:57:31 GMT 2025 , Edited by admin on Wed Apr 02 13:57:31 GMT 2025

PRIMARY

INN

13492

Created by admin on Wed Apr 02 13:57:31 GMT 2025 , Edited by admin on Wed Apr 02 13:57:31 GMT 2025

PRIMARY

From	To
4_138	4_198
4_23	4_88
3_138	3_198
3_23	3_88
2_369	2_427
2_263	2_323
2_222	4_218
2_146	2_202
2_22	2_95
1_369	1_427
1_263	1_323
1_231	2_231
1_228	2_228
1_222	3_218
1_146	1_202
1_22	1_95

Glycosylation Type

MAMMALIAN, AFUCOSYLATED

Glycosylation Link Type	Site
N	1_299
N	2_299

Related Record Type Details


					X3XW6WQP6G

Enzelkitug

ACTIVE MOIETY

Comments:

anti-Homo sapiens CCR8

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL