Pamvatamig

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 18:24:16 GMT 2023` Edited by `admin` on `Sat Dec 16 18:24:16 GMT 2023`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	X3U67W8G5W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Pamvatamig

Official Name

English

Immunoglobulin G1-kappa, anti-[Homo sapiens MET (met proto-oncogene, hepatocyte growth factor (HGF) receptor, HGFR, scatter factor (SF) receptor, HGF/SF receptor, receptor tyrosine-protein kinase c-met, papillary renal cell carcinoma 2, RCCP2)] and anti-

Common Name

English

MCLA-129

Code

English

pamvatamig [INN]

Common Name

English

Gamma1 heavy chain anti-MET Homo sapiens (1-452)[VH (Homo sapiens IGHV7-4-1*02 (95.9%) -(IGHD) -IGHJ5*02 (100%), CDR-IMGT [8.8.16] (26-33.51-58.97-112)) (1-123)-Homo sapiens IGHG1*03, G1m3, nG1m1CH1 R120, E12, M14, G1v72 CH3 D7, E24 (CH1 R120(220) (124-2

Common Name

English

Immunoglobulin G1 [357-aspartic acid,374-glutamic acid,de-C-terminal-lysine], anti-(human hepatocyte growth factor receptor c-Met) (human monoclonal MCLA-129 γ1-chain), disulfide with human monoclonal MCLA-129 κ-chain, (232→231′),(235→234′)-bis

Common Name

English

Code System Code Type Description

CAS

2750004-05-6

Created by admin on Sat Dec 16 18:24:16 GMT 2023 , Edited by admin on Sat Dec 16 18:24:16 GMT 2023

PRIMARY

INN

12549

Created by admin on Sat Dec 16 18:24:16 GMT 2023 , Edited by admin on Sat Dec 16 18:24:16 GMT 2023

PRIMARY

FDA UNII

X3U67W8G5W

Created by admin on Sat Dec 16 18:24:16 GMT 2023 , Edited by admin on Sat Dec 16 18:24:16 GMT 2023

PRIMARY

From	To
4_134	4_194
4_23	4_88
3_134	3_194
3_23	3_88
2_372	2_430
2_266	2_326
2_225	4_214
2_149	2_205
2_22	2_96
1_226	3_214
1_373	1_431
1_267	1_327
1_235	2_234
1_232	2_231
1_150	1_206
1_22	1_96