U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 2C9H6NO7S2.4C4H11N.Cu
Molecular Weight 964.646
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CUPROXOLINE

SMILES

[Cu++].CCNCC.CCNCC.CCNCC.CCNCC.OS(=O)(=O)C1=CC(=C2C=CC=NC2=C1[O-])S(O)(=O)=O.OS(=O)(=O)C3=CC(=C4C=CC=NC4=C3[O-])S(O)(=O)=O

InChI

InChIKey=NHRTVBMNRNCBLQ-UHFFFAOYSA-L
InChI=1S/2C9H7NO7S2.4C4H11N.Cu/c2*11-9-7(19(15,16)17)4-6(18(12,13)14)5-2-1-3-10-8(5)9;4*1-3-5-4-2;/h2*1-4,11H,(H,12,13,14)(H,15,16,17);4*5H,3-4H2,1-2H3;/q;;;;;;+2/p-2

HIDE SMILES / InChI

Molecular Formula C9H6NO7S2
Molecular Weight 304.276
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Cu
Molecular Weight 63.546
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C4H11N
Molecular Weight 73.1368
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Cuproxoline is a copper complex used in a veterinary as a copper supplement. Cuproxoline was also used for the treatment of rheumatoid arthritis, where it was administered by intravenous or intramuscular injections. Clinical studies has shown that cuproxoline therapy gave good results for the treatment of rheumatoid arthritis which had been active for less than a year, even if the patient had become resistant to gold therapy.

Approval Year

Substance Class Chemical
Created
by admin
on Wed Jul 05 23:43:23 UTC 2023
Edited
by admin
on Wed Jul 05 23:43:23 UTC 2023
Record UNII
X36RBY88G2
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CUPROXOLINE
INN   MI  
INN  
Official Name English
BIS(DIHYDROGEN 8-HYDROXY-5,7-QUINOLINEDISULFONATO)COPPER, COMPOUND WITH DIETHYLAMINE (1:4)
Common Name English
CUPROXOLINE [MI]
Common Name English
cuproxoline [INN]
Common Name English
Code System Code Type Description
INN
5029
Created by admin on Wed Jul 05 23:43:23 UTC 2023 , Edited by admin on Wed Jul 05 23:43:23 UTC 2023
PRIMARY
EVMPD
SUB06834MIG
Created by admin on Wed Jul 05 23:43:23 UTC 2023 , Edited by admin on Wed Jul 05 23:43:23 UTC 2023
PRIMARY
CAS
13007-93-7
Created by admin on Wed Jul 05 23:43:23 UTC 2023 , Edited by admin on Wed Jul 05 23:43:23 UTC 2023
PRIMARY
PUBCHEM
71855
Created by admin on Wed Jul 05 23:43:23 UTC 2023 , Edited by admin on Wed Jul 05 23:43:23 UTC 2023
PRIMARY
NCI_THESAURUS
C83641
Created by admin on Wed Jul 05 23:43:23 UTC 2023 , Edited by admin on Wed Jul 05 23:43:23 UTC 2023
PRIMARY
MERCK INDEX
M3930
Created by admin on Wed Jul 05 23:43:23 UTC 2023 , Edited by admin on Wed Jul 05 23:43:23 UTC 2023
PRIMARY Merck Index
SMS_ID
100000083725
Created by admin on Wed Jul 05 23:43:23 UTC 2023 , Edited by admin on Wed Jul 05 23:43:23 UTC 2023
PRIMARY
NCI_THESAURUS
C1505
Created by admin on Wed Jul 05 23:43:23 UTC 2023 , Edited by admin on Wed Jul 05 23:43:23 UTC 2023
CONCEPT Dietary Supplement
FDA UNII
X36RBY88G2
Created by admin on Wed Jul 05 23:43:23 UTC 2023 , Edited by admin on Wed Jul 05 23:43:23 UTC 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE