CUPROXOLINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	2C9H6NO7S2.4C4H11N.Cu
Molecular Weight	964.646
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Cu++].CCNCC.CCNCC.CCNCC.CCNCC.OS(=O)(=O)C1=CC(=C2C=CC=NC2=C1[O-])S(O)(=O)=O.OS(=O)(=O)C3=CC(=C4C=CC=NC4=C3[O-])S(O)(=O)=O

InChI

InChIKey=NHRTVBMNRNCBLQ-UHFFFAOYSA-L

InChI=1S/2C9H7NO7S2.4C4H11N.Cu/c2*11-9-7(19(15,16)17)4-6(18(12,13)14)5-2-1-3-10-8(5)9;4*1-3-5-4-2;/h2*1-4,11H,(H,12,13,14)(H,15,16,17);4*5H,3-4H2,1-2H3;/q;;;;;;+2/p-2

HIDE SMILES / InChI

Molecular Formula	C4H11N
Molecular Weight	73.1368
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C9H6NO7S2
Molecular Weight	304.276
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Cu
Molecular Weight	63.546
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://link.springer.com/article/10.1007/BF00917597 | https://www.tandfonline.com/doi/abs/10.1080/00480169.1959.33319

Cuproxoline is a copper complex used in a veterinary as a copper supplement. Cuproxoline was also used for the treatment of rheumatoid arthritis, where it was administered by intravenous or intramuscular injections. Clinical studies has shown that cuproxoline therapy gave good results for the treatment of rheumatoid arthritis which had been active for less than a year, even if the patient had become resistant to gold therapy.

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 16 19:44:07 UTC 2022` Edited by `admin` on `Fri Dec 16 19:44:07 UTC 2022`
Record UNII	X36RBY88G2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CUPROXOLINE

Official Name

English

BIS(DIHYDROGEN 8-HYDROXY-5,7-QUINOLINEDISULFONATO)COPPER, COMPOUND WITH DIETHYLAMINE (1:4)

Common Name

English

CUPROXOLINE [MI]

Common Name

English

cuproxoline [INN]

Common Name

English

Code System Code Type Description

INN

5029