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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H25ClN2O
Molecular Weight 344.878
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SPICLAMINE

SMILES

ClC1=CC=C(C=C1)[C@@H]2[C@H]3CC[C@H](C3)[C@]24CCC(=N4)N5CCOCC5

InChI

InChIKey=KIYTZWUWLDEAMW-LNKGRISISA-N
InChI=1S/C20H25ClN2O/c21-17-5-2-14(3-6-17)19-15-1-4-16(13-15)20(19)8-7-18(22-20)23-9-11-24-12-10-23/h2-3,5-6,15-16,19H,1,4,7-13H2/t15-,16+,19+,20+/m0/s1

HIDE SMILES / InChI

Molecular Formula C20H25ClN2O
Molecular Weight 344.878
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Spiclamine (Epsilamine) is a hemostatic agent. It was administered to a total of 23 patients with urological diseases, including 8 postoperative cases. Marked effective, effective and ineffecgive responses were observed in 8, 10 and 5 cases respectively, making 78.3 % of effectiveness. In cases of so-called essential renal bleeding and prostatic disease, a particularly beneticial result was obtained making 93.3 % of marked effectiveness. No serious side effects was seen in all cases treated.

Approval Year

PubMed

Substance Class Chemical
Record UNII
X1IEH0PMG2
Record Status Validated (UNII)
Record Version