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Description
Curator's Comment: Description was created based on several sources, including https://www.sumitomo-chem.co.jp/english/rd/report/theses/docs/20050200_imi.pdf

Metofluthrin is a pyrethroid used as an insect repellent. Metofluthrin exhibits the highest potency, being approximately forty times as potent as d-allethrin in a mosquito coil formulation when tested against southern house mosquitoes (Culex quinquefasciatus). Metofluthrin also exhibits a significant vapor action at room temperature.

CNS Activity

Curator's Comment: non-penetrant in rats

Originator

Curator's Comment: Registered in Japan in January 2005

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Mode of action analysis for the synthetic pyrethroid metofluthrin-induced rat liver tumors: evidence for hepatic CYP2B induction and hepatocyte proliferation.
2009 Mar
Patents

Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
Treatment with 50 uM METOFLUTHRIN and 50 uM PB for 72 h increased CYP2B1 mRNA levels in male Wistar rat hepatocytes and CYP2B6 mRNA levels in human hepatocytes.
Substance Class Mixture
Created
by admin
on Sat Dec 16 04:59:38 GMT 2023
Edited
by admin
on Sat Dec 16 04:59:38 GMT 2023
Record UNII
WZX356S299
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
METOFLUTHRIN
ISO   JAN   MI  
Common Name English
(2,3,5,6-TETRAFLUORO-4-METHOXYMETHYLPHENYL)METHYL-2,2-DIMETHYL-3-(1-PROPENYL)CYCLOPROPANECARBOXYLATE
Systematic Name English
METOFLUTHRIN [ISO]
Common Name English
METOFLUTHRIN [JAN]
Common Name English
METOFLUTHRIN [MI]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 109709
Created by admin on Sat Dec 16 04:59:38 GMT 2023 , Edited by admin on Sat Dec 16 04:59:38 GMT 2023
Code System Code Type Description
CAS
240494-70-6
Created by admin on Sat Dec 16 04:59:38 GMT 2023 , Edited by admin on Sat Dec 16 04:59:38 GMT 2023
PRIMARY
ALANWOOD
metofluthrin
Created by admin on Sat Dec 16 04:59:38 GMT 2023 , Edited by admin on Sat Dec 16 04:59:38 GMT 2023
PRIMARY
EPA CompTox
DTXSID4034738
Created by admin on Sat Dec 16 04:59:38 GMT 2023 , Edited by admin on Sat Dec 16 04:59:38 GMT 2023
PRIMARY
MERCK INDEX
m7492
Created by admin on Sat Dec 16 04:59:38 GMT 2023 , Edited by admin on Sat Dec 16 04:59:38 GMT 2023
PRIMARY Merck Index
FDA UNII
WZX356S299
Created by admin on Sat Dec 16 04:59:38 GMT 2023 , Edited by admin on Sat Dec 16 04:59:38 GMT 2023
PRIMARY
WIKIPEDIA
METOFLUTHRIN
Created by admin on Sat Dec 16 04:59:38 GMT 2023 , Edited by admin on Sat Dec 16 04:59:38 GMT 2023
PRIMARY
HSDB
7885
Created by admin on Sat Dec 16 04:59:38 GMT 2023 , Edited by admin on Sat Dec 16 04:59:38 GMT 2023
PRIMARY
Definition References