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Details

Stereochemistry UNKNOWN
Molecular Formula C11H12Cl3N
Molecular Weight 264.579
Optical Activity ( + )
Defined Stereocenters 0 / 1
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of AMFECLORAL, (+)-

SMILES

CC(CC1=CC=CC=C1)\N=C\C(Cl)(Cl)Cl

InChI

InChIKey=VBZDETYCYXPOAK-OVCLIPMQSA-N
InChI=1S/C11H12Cl3N/c1-9(15-8-11(12,13)14)7-10-5-3-2-4-6-10/h2-6,8-9H,7H2,1H3/b15-8+

HIDE SMILES / InChI

Molecular Formula C11H12Cl3N
Molecular Weight 264.579
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 1
Optical Activity ( + / - )

Amphecloral (INN: amfecloral) is a phenethylamine derivative which was patented in 1960 as an amphetamine pro-drug with prolonged duration of action. Amfecloral was used as an appetite suppressant under the trade name Acutran, but is now no longer marketed. It is an anorectic drug with little to no stimulant activity. Amphecloral is metabolized to both d-(S)- and l-(R)-amphetamine.

Approval Year

PubMed

PubMed

TitleDatePubMed
Mode of action of psychomotor stimulant drugs.
1970
Chiral toxicology: it's the same thing...only different.
2009 Jul
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 19:37:12 GMT 2023
Edited
by admin
on Fri Dec 15 19:37:12 GMT 2023
Record UNII
WZS9L0Z92R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMFECLORAL, (+)-
Common Name English
(+)-AMFECLORAL
Common Name English
BENZENEETHANAMINE, .ALPHA.-METHYL-N-(2,2,2-TRICHLOROETHYLIDENE)-, (+)-
Systematic Name English
Code System Code Type Description
FDA UNII
WZS9L0Z92R
Created by admin on Fri Dec 15 19:37:12 GMT 2023 , Edited by admin on Fri Dec 15 19:37:12 GMT 2023
PRIMARY
CAS
25394-63-2
Created by admin on Fri Dec 15 19:37:12 GMT 2023 , Edited by admin on Fri Dec 15 19:37:12 GMT 2023
PRIMARY
Related Record Type Details
RACEMATE -> ENANTIOMER