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Details

Stereochemistry UNKNOWN
Molecular Formula C11H12Cl3N
Molecular Weight 264.579
Optical Activity ( + )
Defined Stereocenters 0 / 1
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of AMFECLORAL, (+)-

SMILES

CC(CC1=CC=CC=C1)\N=C\C(Cl)(Cl)Cl

InChI

InChIKey=VBZDETYCYXPOAK-OVCLIPMQSA-N
InChI=1S/C11H12Cl3N/c1-9(15-8-11(12,13)14)7-10-5-3-2-4-6-10/h2-6,8-9H,7H2,1H3/b15-8+

HIDE SMILES / InChI

Molecular Formula C11H12Cl3N
Molecular Weight 264.579
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 1
Optical Activity ( + / - )

Description

Amphecloral (INN: amfecloral) is a phenethylamine derivative which was patented in 1960 as an amphetamine pro-drug with prolonged duration of action. Amfecloral was used as an appetite suppressant under the trade name Acutran, but is now no longer marketed. It is an anorectic drug with little to no stimulant activity. Amphecloral is metabolized to both d-(S)- and l-(R)-amphetamine.

Originator

Approval Year

PubMed

Substance Class Chemical
Record UNII
WZS9L0Z92R
Record Status Validated (UNII)
Record Version