Solrikitug

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 16:55:09 GMT 2025` Edited by `admin` on `Tue Apr 01 16:55:09 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED
Sequence Type	COMPLETE
Record UNII	WYT4WRY5YF
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Solrikitug

Official Name

English

Gamma1 heavy chain humanized (1-450) [VH (Homo sapiens IGHV1-46*01 (83.7%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, D12, L14 (CH1 K120 (217) (121-218), hinge 1-15 (219-233)

Preferred Name

English

Immunoglobulin G1-kappa, anti-[Homo sapiens CRLF2 (cytokine receptor like factor 2,TSLP, thymic stromal lymphopoietin)], humanized monoclonal antibody

Common Name

English

solrikitug [INN]

Common Name

English

SOLRIKITUG [USAN]

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C203159

Created by admin on Tue Apr 01 16:55:09 GMT 2025 , Edited by admin on Tue Apr 01 16:55:09 GMT 2025

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FDA UNII

WYT4WRY5YF

Created by admin on Tue Apr 01 16:55:09 GMT 2025 , Edited by admin on Tue Apr 01 16:55:09 GMT 2025

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INN

12752

Created by admin on Tue Apr 01 16:55:09 GMT 2025 , Edited by admin on Tue Apr 01 16:55:09 GMT 2025

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SMS_ID

300000049647

Created by admin on Tue Apr 01 16:55:09 GMT 2025 , Edited by admin on Tue Apr 01 16:55:09 GMT 2025

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CAS

2768721-24-8

Created by admin on Tue Apr 01 16:55:09 GMT 2025 , Edited by admin on Tue Apr 01 16:55:09 GMT 2025

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USAN

NO-12

Created by admin on Tue Apr 01 16:55:09 GMT 2025 , Edited by admin on Tue Apr 01 16:55:09 GMT 2025

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From	To
1_22	1_96
2_22	2_96
2_147	2_203
2_223	4_214
2_264	2_324
1_147	1_203
2_370	2_428
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_223	3_214
1_229	2_229
1_232	2_232
1_264	1_324
1_370	1_428

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_300
N	2_300

Related Record Type Details


					GT0IL38SP4

THYMIC STROMAL LYMPHOPOIETIN

TARGET->LIGAND

Amount:

Related Record Type Details


					WYT4WRY5YF

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_450] [2_450]	C-TERMINUS	K		LYSINE	K3Z4F929H6
N-TERMINAL MODIFICATION	[1_1] [2_1]		GLUTAMINE		PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:CALCULATED	CHEMICAL