U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class
Concept
Record UNII
WYJ05POC5C
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GWN-323
Code English
GWN 323 [WHO-DD]
Common Name English
GWN323
Code English
ANTI-GITR MONOCLONAL ANTIBODY GWN 323
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C128058
Created by admin on Sat Dec 16 14:16:16 GMT 2023 , Edited by admin on Sat Dec 16 14:16:16 GMT 2023
NCI_THESAURUS C129822
Created by admin on Sat Dec 16 14:16:16 GMT 2023 , Edited by admin on Sat Dec 16 14:16:16 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C128028
Created by admin on Sat Dec 16 14:16:16 GMT 2023 , Edited by admin on Sat Dec 16 14:16:16 GMT 2023
PRIMARY
FDA UNII
WYJ05POC5C
Created by admin on Sat Dec 16 14:16:16 GMT 2023 , Edited by admin on Sat Dec 16 14:16:16 GMT 2023
PRIMARY
This is a non-substance concept
Related Record Type Details
TARGET -> AGONIST
Binds to and activates GITRs found on multiple types of T-cells. This stimulates the immune system, induces both the activation and proliferation of tumor-antigen-specific T effector cells (Teff), and suppresses the function of activated T regulatory cells (Tregs).
Related Record Type Details
ACTIVE MOIETY
This is a non-substance concept