ISPECTAMAB DEBOTANSINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 00:45:02 GMT 2025` Edited by `admin` on `Wed Apr 02 00:45:02 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Origin	humanized
Sequence Type	COMPLETE
Record UNII	WY39ZX6NZU
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ISPECTAMAB DEBOTANSINE

Official Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN B-CELL MATURATION ANTIGEN) (HUMAN MONOCLONAL SP8893 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL SP8893 .KAPPA.-CHAIN, DIMER, 186,410-BIS(4-((8-(3-AMINO-1-OXOPROPYL)-8,9-DIHYDRO-1H(OR 3H)-DIBENZO(B,F)-1,2,3-TRIAZOLO(4,5

Preferred Name

English

ispectamab debotansine [INN]

Common Name

English

Ispectamab debotansine [WHO-DD]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

802520

Created by admin on Wed Apr 02 00:45:02 GMT 2025 , Edited by admin on Wed Apr 02 00:45:02 GMT 2025

Code System Code Type Description

FDA UNII

WY39ZX6NZU

Created by admin on Wed Apr 02 00:45:02 GMT 2025 , Edited by admin on Wed Apr 02 00:45:02 GMT 2025

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SMS_ID

300000042088

Created by admin on Wed Apr 02 00:45:02 GMT 2025 , Edited by admin on Wed Apr 02 00:45:02 GMT 2025

PRIMARY

NCI_THESAURUS

C170915

Created by admin on Wed Apr 02 00:45:02 GMT 2025 , Edited by admin on Wed Apr 02 00:45:02 GMT 2025

PRIMARY

INN

12079

Created by admin on Wed Apr 02 00:45:02 GMT 2025 , Edited by admin on Wed Apr 02 00:45:02 GMT 2025

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CAS

2413386-21-5

Created by admin on Wed Apr 02 00:45:02 GMT 2025 , Edited by admin on Wed Apr 02 00:45:02 GMT 2025

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From	To
1_23	1_97
2_23	2_97
2_150	2_206
2_226	4_215
2_267	2_327
1_150	1_206
2_373	2_431
3_24	3_89
3_135	3_195
4_24	4_89
4_135	4_195
1_226	3_215
1_232	2_232
1_235	2_235
1_267	1_327
1_373	1_431

Related Record Type Details


					WY39ZX6NZU

ISPECTAMAB DEBOTANSINE

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_186] [1_410] [2_186] [2_410]	SITE_SPECIFIC		Amount:	UNSPECIFIED SUBSTANCE	ee5ffd5e (not in database)

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL