Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C36H49N3O22Sb3.Na |
| Molecular Weight | 1264.051 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 15 / 15 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].OC[C@H]1O[C@@H](NC2=CC=C(C=C2)[Sb](O)(=O)O[Sb](=O)(O[Sb]([O-])(=O)C3=CC=C(N[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=C3)C5=CC=C(N[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C=C5)[C@H](O)[C@@H](O)[C@@H]1O
InChI
InChIKey=CTZKOPZYANZEBA-PLJZAMQKSA-M
InChI=1S/3C12H16NO5.Na.H2O.6O.3Sb/c3*14-6-8-9(15)10(16)11(17)12(18-8)13-7-4-2-1-3-5-7;;;;;;;;;;;/h3*2-5,8-17H,6H2;;1H2;;;;;;;;;/q;;;+1;;;;;;;-1;;;+1/p-1/t3*8-,9-,10+,11-,12-;;;;;;;;;;;/m111.........../s1
| Molecular Formula | C36H49N3O22Sb3 |
| Molecular Weight | 1241.061 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 15 / 15 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
| Molecular Formula | Na |
| Molecular Weight | 22.9898 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Stibamine Glucoside is a nitrogen glucoside of p-aminophenylstibinate of sodium useful for the treatment of leishmaniasis and visceral leishmaniasis also known as kala-azar black fever Stibamine Glucoside is administered by slow i.v or deep i.m. injection. Some 80% of a dose is recov¬ered in the urine on 24 h. Elimination from the plasma is biphasic, the half-life of the initial phase being 2 h and that of the subsequent phase 76 h. In high dose car¬diac, renal or hepatic toxicity may occur. Stibamine Glucoside is no longer marketed due to safety reason.
Originator
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:51:58 GMT 2023
by
admin
on
Fri Dec 15 15:51:58 GMT 2023
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| Record UNII |
WXW6I2Y86R
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| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C276
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C152429
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