Ontasameran

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Wed Apr 02 07:40:09 GMT 2025` Edited by `admin` on `Wed Apr 02 07:40:09 GMT 2025`
Nucleic Acid Type	mRNA VACCINE
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	WVT3HJM1DN
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FixVac COMPONENT ONTASAMERAN

Preferred Name

English

Ontasameran

Official Name

English

MESSENGER RNA ENCODING TRANSMEMBRANE PHOSPHATASE WITH TENSIN HOMOLOGY (TPTE). MESSENGER RNA (MRNA), 5'-CAPPED, ENCODING CODON-OPTIMISED TRANSMEMBRANE PHOSPHATASE WITH TENSIN HOMOLOGY (TPTE; CANCER/TESTIS ANTIGEN 44) EXPRESSED AS A FUSION PROTEIN COMPRISI

Common Name

English

RBL-004.3

Code

English

BNT111 COMPONENT ONTASAMERAN

Code

English

BNT-111 COMPONENT ONTASAMERAN

Common Name

English

ontasameran [INN]

Common Name

English

RBL004.3

Code

English

RNA (recombinant [1,2-[m7Gm-p-[P(R)]-sp-p-G]]-capped human transmembrane phosphatase with tensin homology (TPTE)-specifying poly(A)-tailed messenger RBL004.3), inner salt

Common Name

English

ONTASAMERAN [USAN]

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C175832

Created by admin on Wed Apr 02 07:40:09 GMT 2025 , Edited by admin on Wed Apr 02 07:40:09 GMT 2025

PRIMARY

INN

11480

Created by admin on Wed Apr 02 07:40:09 GMT 2025 , Edited by admin on Wed Apr 02 07:40:09 GMT 2025

PRIMARY

USAN

KL-143

Created by admin on Wed Apr 02 07:40:09 GMT 2025 , Edited by admin on Wed Apr 02 07:40:09 GMT 2025

PRIMARY

SMS_ID

300000024536

Created by admin on Wed Apr 02 07:40:09 GMT 2025 , Edited by admin on Wed Apr 02 07:40:09 GMT 2025

PRIMARY

CAS

2348561-00-0

Created by admin on Wed Apr 02 07:40:09 GMT 2025 , Edited by admin on Wed Apr 02 07:40:09 GMT 2025

PRIMARY

FDA UNII

WVT3HJM1DN

Created by admin on Wed Apr 02 07:40:09 GMT 2025 , Edited by admin on Wed Apr 02 07:40:09 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
D-Ribose (RNA)	1_1-1_2675	2675 / 2675

Linkage	Site Range	Site Count
Phosphate	1_2-1_2675	2674 / 2674

Related Record Type Details


					MA53Z5C2K6

HUMAN MELANOMA CELL

TARGET->VACCINE ANTIGEN

Amount:

Related Record Type Details


					WVT3HJM1DN

ACTIVE MOIETY

Comments:

Immunomodulator, antineoplastic

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOTIDE SUBSTITUTION	[1_1]	5'-TERMINUS			UNSPECIFIED SUBSTANCE	fd4a4c35 (not in database)