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Details

Stereochemistry ABSOLUTE
Molecular Formula C34H46O18
Molecular Weight 742.7182
Optical Activity UNSPECIFIED
Defined Stereocenters 14 / 14
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ELEUTHEROSIDE D

SMILES

[H][C@@]12CO[C@H](C3=CC(OC)=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(OC)=C3)[C@@]1([H])CO[C@@H]2C5=CC(OC)=C(O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(OC)=C5

InChI

InChIKey=FFDULTAFAQRACT-LHJOJEKWSA-N
InChI=1S/C34H46O18/c1-43-17-5-13(6-18(44-2)31(17)51-33-27(41)25(39)23(37)21(9-35)49-33)29-15-11-48-30(16(15)12-47-29)14-7-19(45-3)32(20(8-14)46-4)52-34-28(42)26(40)24(38)22(10-36)50-34/h5-8,15-16,21-30,33-42H,9-12H2,1-4H3/t15-,16+,21-,22-,23-,24-,25+,26+,27-,28-,29-,30-,33+,34+/m1/s1

HIDE SMILES / InChI

Molecular Formula C34H46O18
Molecular Weight 742.7182
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 14 / 14
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Eleutheroside D is an eleutheroside, a compound found in roots and stems of Eleutherococcus senticosus, the Siberian ginseng. Eleutheroside D and its diastereoisomer Eleutheroside E thought to be the most pharmacologically active eleutherosides. Placebo-controlled trial tested the effect of eleuthero extract (eleutheroside B in combination with eleutheroside B) on maximal working capacity by bicycle ergometry. Total work and time to exhaustion were significantly greater after eleuthero, compared with placebo phase and baseline.

Originator

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
Two ml of Eleutherococcus ethanol extract (0.24 mg of Eleutheroside D) once in the morning and again in the evening (0.5 h before meal) for 8 consecutive days
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
WVS8LR64R4
Record Status Validated (UNII)
Record Version