U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:23:01 GMT 2023
Edited
by admin
on Sat Dec 16 14:23:01 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
WV9KZ9PS1A
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ITEPEKIMAB
USAN   INN  
Official Name English
ITEPEKIMAB [USAN]
Common Name English
IMMUNOGLOBULIN IGG4 (230-PROLINE), ANTI-(HUMAN INTERLEUKIN 33) (HUMAN MONOCLONAL REGN3500 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL REGN3500 .KAPPA.-CHAIN, DIMER
Common Name English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS IL33 (INTERLEUKIN 33, INTERLEUKIN-1 FAMILY MEMBER 11, IL1F11, NUCLEAR FACTOR FOR HIGH ENDOTHELIAL VENULES, NF-HEV)), MONOCLONAL ANTIBODY; GAMMA4 HEAVY CHAIN (1-449) (VH (HOMO SAPIENS IGHV3-23*04 (88.8%)-(IGHD)
Systematic Name English
Itepekimab [WHO-DD]
Common Name English
SAR440340
Code English
SAR-440340
Code English
REGN3500
Code English
REGN-3500
Code English
itepekimab [INN]
Common Name English
Code System Code Type Description
NCI_THESAURUS
C174938
Created by admin on Sat Dec 16 14:23:01 GMT 2023 , Edited by admin on Sat Dec 16 14:23:01 GMT 2023
PRIMARY
FDA UNII
WV9KZ9PS1A
Created by admin on Sat Dec 16 14:23:01 GMT 2023 , Edited by admin on Sat Dec 16 14:23:01 GMT 2023
PRIMARY
INN
11333
Created by admin on Sat Dec 16 14:23:01 GMT 2023 , Edited by admin on Sat Dec 16 14:23:01 GMT 2023
PRIMARY
CAS
2226742-52-3
Created by admin on Sat Dec 16 14:23:01 GMT 2023 , Edited by admin on Sat Dec 16 14:23:01 GMT 2023
PRIMARY
USAN
JK-09
Created by admin on Sat Dec 16 14:23:01 GMT 2023 , Edited by admin on Sat Dec 16 14:23:01 GMT 2023
PRIMARY
From To
1_22 1_96
1_149 1_205
1_263 1_323
1_369 1_427
1_136 3_214
1_228 2_228
1_231 2_231
2_22 2_96
2_136 4_214
2_149 2_205
2_263 2_323
2_369 2_427
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_299
N 2_299
Related Record Type Details
TARGET -> INHIBITOR
IC50
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL