EPLONTERSEN SODIUM

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 14:39:50 GMT 2023` Edited by `admin` on `Sat Dec 16 14:39:50 GMT 2023`
Nucleic Acid Type	OLIGONUCLEOTIDE
Nucleic Acid Subtype
Sequence Type	COMPLETE
Record UNII	WSP2DHR2BD
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

EPLONTERSEN SODIUM

Official Name

English

EPLONTERSEN SODIUM [USAN]

Common Name

English

ISIS-682884

Code

English

AKCEA-TTR-LRX SODIUM

Code

English

ION-682884

Code

English

IONIS-TTR-LRX SODIUM

Code

English

DNA, D((2'-O-(2-METHOXYETHYL))M5RU-SP-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))M5RU-(2'-O-(2-METHOXYETHYL))RG-G-SP-T-SP-T-SP-A-SP-M5C-SP-A-SP-T-SP-G-SP-A-SP-A-SP-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))M5RU-

Systematic Name

English

ION-682884 SODIUM

Code

English

ALL-P-AMBO-5-O-(((6-(5-((TRIS(3-(6-(2-ACETAMIDO-2-DEOXY-.BETA.-D-GALACTOPYRANOSYLOXY)HEXYLAMINO)-3-OXOPROPOXYMETHYL))METHYL)AMINO-5-OXOPENTANAMIDO)HEXOXY))PHOSPHO)-2-O-(2-METHOXYETHYL)-5-METHYL-P-THIOURIDYLYL-(3-O->5-O)-2-O-(2-METHOXYETHYL)-5-METHYLCYTID

Common Name

English

Code System Code Type Description

FDA UNII

WSP2DHR2BD

Created by admin on Sat Dec 16 14:39:50 GMT 2023 , Edited by admin on Sat Dec 16 14:39:50 GMT 2023

PRIMARY

NCI_THESAURUS

C174936

Created by admin on Sat Dec 16 14:39:50 GMT 2023 , Edited by admin on Sat Dec 16 14:39:50 GMT 2023

PRIMARY

CAS

2131025-75-5

Created by admin on Sat Dec 16 14:39:50 GMT 2023 , Edited by admin on Sat Dec 16 14:39:50 GMT 2023

PRIMARY

USAN

GH-149

Created by admin on Sat Dec 16 14:39:50 GMT 2023 , Edited by admin on Sat Dec 16 14:39:50 GMT 2023

PRIMARY

Sugar	Site Range	Site Count
2'-O-Methoxyethyl ribose	1_1-1_5;1_16-1_20	10 / 20
Deoxyribose (DNA)	1_6-1_15	10 / 20

Linkage	Site Range	Site Count
	1_3-1_6;1_17-1_18	6 / 19
Sodium Phosporothioate	1_2;1_7-1_16;1_19-1_20	13 / 19

Related Record Type Details


					0GRZ0F5XJ6

EPLONTERSEN

PARENT -> SALT/SOLVATE

Amount:


					2COU0B578R

TRANSTHYRETIN

TARGET->INHIBITOR OF EXPRESSION

Related Record Type Details


					0GRZ0F5XJ6

EPLONTERSEN

ACTIVE MOIETY