U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:17:49 GMT 2023
Edited
by admin
on Sat Dec 16 14:17:49 GMT 2023
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type BISPECIFIC T CELL ENGAGER
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
WR4J8FV2SM
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ETEVRITAMAB
INN  
Official Name English
ANTI-EGFRVIII/CD3 BITE ANTIBODY AMG 596
Common Name English
IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR VARIANT III) (HUMAN MONOCLONAL EGFRVIII BISPECIFIC 1 SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN A
Common Name English
AMG596
Code English
AMG-596
Code English
etevritamab [INN]
Common Name English
IMMUNOGLOBULIN SCFV-SCFV, ANTI-(HOMO SAPIENS EGFR (EPIDERMAL GROWTH FACTOR RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB) VARIANT III (EGFRVIII)) AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), MONOCLONAL ANTIBODY SINGLE
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 634718
Created by admin on Sat Dec 16 14:17:49 GMT 2023 , Edited by admin on Sat Dec 16 14:17:49 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C146824
Created by admin on Sat Dec 16 14:17:49 GMT 2023 , Edited by admin on Sat Dec 16 14:17:49 GMT 2023
PRIMARY
INN
11418
Created by admin on Sat Dec 16 14:17:49 GMT 2023 , Edited by admin on Sat Dec 16 14:17:49 GMT 2023
PRIMARY
CAS
2329692-74-0
Created by admin on Sat Dec 16 14:17:49 GMT 2023 , Edited by admin on Sat Dec 16 14:17:49 GMT 2023
PRIMARY
FDA UNII
WR4J8FV2SM
Created by admin on Sat Dec 16 14:17:49 GMT 2023 , Edited by admin on Sat Dec 16 14:17:49 GMT 2023
PRIMARY
From To
1_22 1_96
1_44 1_244
1_162 1_232
1_279 1_355
1_419 1_487
Related Record Type Details
TARGET -> ACTIVATOR
TARGET->LIGAND
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL