Frexalimab

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:45:28 GMT 2023` Edited by `admin` on `Sat Dec 16 14:45:28 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	WO7SFK0ENJ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Frexalimab

Official Name

English

FREXALIMAB [USAN]

Common Name

English

INX 021-56

Code

English

INX 021

Code

English

frexalimab [INN]

Common Name

English

XC 01129

Code

English

SAR-441344

Code

English

Immunoglobulin G1 (272-arginine,325-alanine), anti-(human CD40 ligand) (human-mus musculus monoclonal SAR441344 gamma1-chain), disulfide with human-mus musculus monoclonal SAR441344 kappa-chain, dimer

Common Name

English

SAR441344

Code

English

Code System Code Type Description

USAN

LM-99

Created by admin on Sat Dec 16 14:45:28 GMT 2023 , Edited by admin on Sat Dec 16 14:45:28 GMT 2023

PRIMARY

NCI_THESAURUS

C190493

Created by admin on Sat Dec 16 14:45:28 GMT 2023 , Edited by admin on Sat Dec 16 14:45:28 GMT 2023

PRIMARY

INN

11963

Created by admin on Sat Dec 16 14:45:28 GMT 2023 , Edited by admin on Sat Dec 16 14:45:28 GMT 2023

PRIMARY

FDA UNII

WO7SFK0ENJ

Created by admin on Sat Dec 16 14:45:28 GMT 2023 , Edited by admin on Sat Dec 16 14:45:28 GMT 2023

PRIMARY

CAS

2515463-86-0

Created by admin on Sat Dec 16 14:45:28 GMT 2023 , Edited by admin on Sat Dec 16 14:45:28 GMT 2023

PRIMARY

From	To
1_22	1_95
2_22	2_95
2_147	2_203
2_223	4_214
2_264	2_324
1_147	1_203
2_370	2_428
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_223	3_214
1_229	2_229
1_232	2_232
1_264	1_324
1_370	1_428

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_300
N	2_300

Related Record Type Details


					T169OM1T8L

CD40 LIGAND RECOMBINANT

TARGET -> INHIBITOR

Amount:


					YUF12AXR3B

CD40 LIGAND SOLUBLE

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					WO7SFK0ENJ

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL