U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Wed Apr 02 19:53:22 GMT 2025
Edited
by admin
on Wed Apr 02 19:53:22 GMT 2025
Protein Type PEPTIDE
Protein Sub Type GLUCAGON-LIKE PEPTIDE
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
WNC7GC5MM7
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MEDI-7219
Code English
MEDI-7219 (GLP?1 receptor agonist)
Preferred Name English
MEDI7219
Code English
Code System Code Type Description
FDA UNII
WNC7GC5MM7
Created by admin on Wed Apr 02 19:53:22 GMT 2025 , Edited by admin on Wed Apr 02 19:53:22 GMT 2025
PRIMARY
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ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO_ACID_SUBSTITUTION [1_2] A .ALPHA.-AMINOISOBUTYRIC ACID 1E7ZW41IQU
AMINO_ACID_SUBSTITUTION [1_11] S D-2-Methylserine 5DV2ZZJ5JK
AMINO_ACID_SUBSTITUTION [1_30] C-TERMINUS G GLYCINAMIDE 4JDT453NWO
AMINO_ACID_SUBSTITUTION [1_20] K 2-Methyl-L-lysine G24VRC2EBB
AMINO_ACID_SUBSTITUTION [1_6] [1_22] F L-.ALPHA.-METHYLPHENYLALANINE W4V7K5BM5T
AMINO_ACID_SUBSTITUTION [1_13] [1_25] K Lysyl-peg-lauroyl-modified amino acid H3EN7GDD53
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL