ALTENUSIN

COC1=CC(C2=C(C)C=C(O)C(O)=C2)=C(C(O)=O)C(O)=C1

InChIKey=ADPBTBPPIIKLEH-UHFFFAOYSA-N

InChI=1S/C15H14O6/c1-7-3-11(16)12(17)6-9(7)10-4-8(21-2)5-13(18)14(10)15(19)20/h3-6,16-18H,1-2H3,(H,19,20)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
Bifunctional ligase/repressor BirA 1 Target ID: P06709 Gene ID: 948469.0 Gene Symbol: birA Target Organism: Escherichia coli (strain K12) Sources: https://www.ncbi.nlm.nih.gov/pubmed/29376540	Inhibitor 8504
Bile acid receptor FXR 29 Target ID: CHEMBL2047 Sources: https://www.ncbi.nlm.nih.gov/pubmed/28739572	Agonist 2752	3.2 µM [EC50]
Trypanothione reductase 5 Target ID: CHEMBL5131 Sources: https://www.ncbi.nlm.nih.gov/pubmed/18557945	Inhibitor 8504	4.3 µM [IC50]

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:22:31 GMT 2025` Edited by `admin` on `Mon Mar 31 19:22:31 GMT 2025`
Record UNII	WM31322YA1
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

ALTENUSIN

Common Name

English

ALUTENUSIN

Preferred Name

English

(1,1'-BIPHENYL)-2-CARBOXYLIC ACID, 3,4',5'-TRIHYDROXY-5-METHOXY-2'-METHYL-

Systematic Name

English

3,4',5'-TRIHYDROXY-5-METHOXY-2'-METHYL(1,1'-BIPHENYL)-2-CARBOXYLIC ACID

Systematic Name

English

Code System Code Type Description

FDA UNII

WM31322YA1