U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C5H9NO
Molecular Weight 99.1311
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2-PIPERIDONE

SMILES

O=C1CCCCN1

InChI

InChIKey=XUWHAWMETYGRKB-UHFFFAOYSA-N
InChI=1S/C5H9NO/c7-5-3-1-2-4-6-5/h1-4H2,(H,6,7)

HIDE SMILES / InChI

Molecular Formula C5H9NO
Molecular Weight 99.1311
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Identification of 2-piperidone as a biomarker of CYP2E1 activity through metabolomic phenotyping.
2013-09
5-[(E)-2-Fluoro-benzyl-idene]-8-(2-fluoro-phen-yl)-2-hy-droxy-10-methyl-3,10-di-aza-hexa-cyclo-[10.7.1.1.0.0.0]henicosa-1(20),12,14,16,18-pentaen-6-one.
2010-12-24
Investigating the activity of 2-substituted alkyl-6-(2,5-dioxopyrrolidin-1-yl)hexanoates as skin penetration enhancers.
2010-12-15
Chemopreventive potential of 3-[2,6-bis(4-fluorophenyl)-3-methylpiperidin-4-ylideneamino]-2-thioxoimidazolidin-4-one on 7,12-dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch carcinogenesis.
2010-12
Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization.
2010-11-11
11-[(E)-4-Bromo-benzyl-idene]-8-(4-bromo-phen-yl)-14-hy-droxy-3,13-diaza-hepta-cyclo-[13.7.1.1.0.0.0.0]tetra-cosa-1(22),15,17,19(23),20-pentaen-10-one.
2010-10-23
5-[(E)-Benzyl-idene]-2-hy-droxy-10-methyl-8-phenyl-3,10-diazahexa-cyclo-[10.7.1.1.0.0.0]henicosa-1(19),12(20),13,15,17-pentaen-6-one ethanol 0.25-solvate 0.6-hydrate.
2010-10-09
Fractionation and identification of organic nitrogen species from bio-oil produced by fast pyrolysis of sewage sludge.
2010-10
2-Hy-droxy-16-[(E)-4-methyl-benzyl-idene]-13-(4-methyl-phen-yl)-12-phenyl-1,11-diaza-penta-cyclo-[12.3.1.0.0.0]octa-deca-3(8),4,6-triene-9,15-dione.
2010-07-24
16-[(E)-Benzyl-idene]-2-hy-droxy-12,13-diphenyl-1,11-diaza-penta-cyclo-[12.3.1.0.0.0]octa-deca-3(8),4,6-triene-9,15-dione.
2010-07-24
3,3-Bis[(4-chloro-phen-yl)sulfan-yl]-1-methyl-piperidin-2-one.
2010-06-30
Differentiation of Boc-protected alpha,delta-/delta,alpha- and beta,delta-/delta,beta-hybrid peptide positional isomers by electrospray ionization tandem mass spectrometry.
2010-06
1-(2-Bromo-acet-yl)-3-methyl-2,6-diphenyl-piperidin-4-one.
2010-05-29
19-[(E)-4-Chloro-benzyl-idene]-16-(4-chloro-phen-yl)-2-hydr-oxy-1,11-diaza-hexa-cyclo-[15.3.1.0.0.0.0]henicosa-3(8),4,6-triene-9,18-dione.
2010-05-26
r-2,c-6-Bis(2-methoxy-phen-yl)-t-3,t-5-dimethyl-piperidin-4-one acetic acid solvate.
2010-05-22
2-Hydr-oxy-16-[(E)-4-hydr-oxy-3-methoxy-benzyl-idene]-13-(4-hydr-oxy-3-methoxy-phen-yl)-11-methyl-1,11-diaza-penta-cyclo-[12.3.1.0.0.0]octa-deca-3(8),4,6-triene-9,15-dione.
2010-05-15
Synthesis of spirocyclic carbazole- and acridine-lactams.
2010-04-21
Asymmetric synthesis of a potent, aminopiperidine-fused imidazopyridine dipeptidyl peptidase IV inhibitor.
2010-03-05
Preliminary studies into the characterization of chemical markers of decomposition for geoforensics.
2010-03-01
4'-(2,4-Dichloro-phen-yl)-1,1'-dimethyl-piperidine-3-spiro-3'-pyrrolidine-2'-spiro-3''-indoline-4,2''-dione.
2010-02-27
Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors.
2009-12-31
(5''E)-1''-Benzyl-1'-methyl-5''-[4-(methyl-sulfan-yl)benzyl-idene]-4'-[4-(methyl-sulfan-yl)phen-yl]dispiro-[indoline-3,2'-pyrrolidine-3',3''-piperidine]-2,4''-dione dichloro-methane solvate.
2009-12-24
Methyl 7,8-diacet-oxy-11-oxo-5-(2-oxo-pyrrolidin-1-yl)-7,9-epoxy-cyclo-penta-[4,5]pyrido[1,2-a]quinoline-10-carboxyl-ate sesquihydrate.
2009-12-19
1,1'-(p-Phenyl-enedimethyl-ene)dipiperidin-4-one.
2009-12-16
Dimethyl 11,13-dimethyl-16-[1,2-bis-(methoxy-carbon-yl)ethen-yl]-12-oxo-16,17-dioxa-18-aza-hexa-cyclo-[7.5.1.1.1.1.0]octa-deca-2,7-diene-2,3-dicarboxyl-ate.
2009-11-28
Ethyl 4-hydr-oxy-1-(2-morpholinopro-pano-yl)-2,6-diphenyl-1,2,5,6-tetra-hydro-pyridin-3-carboxyl-ate.
2009-11-28
Asymmetric total synthesis of (-)-awajanomycin.
2009-11-19
(3E,5E)-3,5-Bis(4-allyl-oxybenzyl-idene)-1-benzyl-piperidin-4-one.
2009-11-11
2,6-Bis(3-methoxy-phen-yl)-3-methyl-piperidin-4-one.
2009-11-04
Methyl 4,5-diacet-oxy-1-oxo-2-phenyl-perhydro-4,6-epoxy-cyclo-penta-[c]pyridine-7-carboxyl-ate ethanol solvate.
2009-11-04
Synthesis of sigma receptor ligands with unsymmetrical spiro connection of the piperidine moiety.
2009-11
c-3,t-3-Dimethyl-4-oxo-r-2,c-6-diphenyl-piperidine-1-carboxamide.
2009-10-23
(3E,5E)-1-Benzyl-3,5-dibenzyl-idenepiperidin-4-one.
2009-10-17
(3E,5E)-1-Benzyl-3,5-bis-(2-fluoro-benzyl-idene)piperidin-4-one.
2009-10-07
2,3,6-Triphenyl-piperidin-4-one.
2009-09-12
1-Benzyl-3,5-bis-(2-thienylmethyl-ene)-4-piperidone.
2009-09-05
1-Chloro-acetyl-2,6-bis-(2-methoxy-phen-yl)-3,5-dimethyl-piperidin-4-one.
2009-08-29
N-Cyclo-hexyl-5H,7H-13,15-dimethyl-9-nitro-5-oxophenanthrido[4,4a,5-bc][1,4]benzoxazepine-7-carboxamide.
2009-07-25
1-Chloro-acetyl-2,6-bis-(3-fluoro-phen-yl)piperidin-4-one.
2009-07-25
r-2,c-6-Bis(4-methoxy-phenyl)-c-3,t-3-dimethyl-1-nitro-sopiperidin-4-one.
2009-05-29
13-Hydr-oxy-4,16-dimethyl-4,16-diaza-penta-cyclo-[12.3.1.0.0.0]octa-deca-7(12),8,10-triene-6,18-dione.
2009-04-30
1-Acryloyl-2,6-bis-(4-chloro-phen-yl)-3,5-dimethyl-piperidin-4-one.
2009-04-08
1-Methyl-3,5-bis-[(E)-(3-methyl-2-thienyl)methyl-ene]piperidin-4-one monohydrate.
2009-03-28
1,3-Dimethyl-2,6-diphenyl-piperidin-4-one.
2009-01-31
1-Bromo-acetyl-2,6-bis-(4-methoxy-phen-yl)-3,5-dimethyl-piperidin-4-one.
2008-09-27
r-2,c-6-Bis(3-methoxy-phen-yl)-t-3,t-5-dimethyl-piperidin-4-one.
2008-07-31
1-Methyl-3-phenyl-sulfonyl-2-piperidone.
2008-04-16
3-[(E)-4-Methoxy-benzyl-idene]-1-methyl-piperidin-4-one.
2008-02-06
r-2,c-6-Bis(4-fluoro-phen-yl)-t-3,t-5-dimethyl-piperidin-4-one.
2008-01-11
3-(4-Chloro-phen-yl)-7-methyl-4-(4-methyl-phen-yl)-1-oxa-2,7-diaza-spiro-[4.5]dec-2-en-10-one.
2008-01-09
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:48:43 GMT 2025
Edited
by admin
on Mon Mar 31 19:48:43 GMT 2025
Record UNII
WLN0GQQ6EK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NSC-18894
Preferred Name English
2-PIPERIDONE
Systematic Name English
.ALPHA.-PIPERIDONE
Common Name English
2-OXOPIPERIDINE
Common Name English
5-PENTANOLACTAM
Common Name English
2-PIPERIDINONE
Common Name English
NSC-2305
Code English
VALEROLACTIM
Common Name English
Code System Code Type Description
PUBCHEM
12665
Created by admin on Mon Mar 31 19:48:43 GMT 2025 , Edited by admin on Mon Mar 31 19:48:43 GMT 2025
PRIMARY
EPA CompTox
DTXSID1060976
Created by admin on Mon Mar 31 19:48:43 GMT 2025 , Edited by admin on Mon Mar 31 19:48:43 GMT 2025
PRIMARY
ECHA (EC/EINECS)
211-622-9
Created by admin on Mon Mar 31 19:48:43 GMT 2025 , Edited by admin on Mon Mar 31 19:48:43 GMT 2025
PRIMARY
CAS
675-20-7
Created by admin on Mon Mar 31 19:48:43 GMT 2025 , Edited by admin on Mon Mar 31 19:48:43 GMT 2025
PRIMARY
WIKIPEDIA
2-Piperidone
Created by admin on Mon Mar 31 19:48:43 GMT 2025 , Edited by admin on Mon Mar 31 19:48:43 GMT 2025
PRIMARY
NSC
18894
Created by admin on Mon Mar 31 19:48:43 GMT 2025 , Edited by admin on Mon Mar 31 19:48:43 GMT 2025
PRIMARY
FDA UNII
WLN0GQQ6EK
Created by admin on Mon Mar 31 19:48:43 GMT 2025 , Edited by admin on Mon Mar 31 19:48:43 GMT 2025
PRIMARY
NSC
2305
Created by admin on Mon Mar 31 19:48:43 GMT 2025 , Edited by admin on Mon Mar 31 19:48:43 GMT 2025
PRIMARY
CHEBI
77761
Created by admin on Mon Mar 31 19:48:43 GMT 2025 , Edited by admin on Mon Mar 31 19:48:43 GMT 2025
PRIMARY