ALLOCUPREIDE SODIUM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H10N2O2S.Cu.Na
Molecular Weight	320.81
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].[Cu+].[O-]C(=O)C1=CC(NC(=S)[N-]CC=C)=CC=C1

InChI

InChIKey=YDUVCZIUYAFEPZ-UHFFFAOYSA-L

InChI=1S/C11H12N2O2S.Cu.Na/c1-2-6-12-11(16)13-9-5-3-4-8(7-9)10(14)15;;/h2-5,7H,1,6H2,(H3,12,13,14,15,16);;/q;2*+1/p-2

HIDE SMILES / InChI

Molecular Formula	Cu
Molecular Weight	63.546
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C11H11N2O2S
Molecular Weight	235.282
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14878353 | https://www.drugfuture.com/chemdata/allocupreide-sodium.html | https://www.ncbi.nlm.nih.gov/pubmed/14873976 | https://www.ncbi.nlm.nih.gov/pubmed/18888679 | https://www.ncbi.nlm.nih.gov/pubmed/13239940

Allocupreide is a copper(l) complex used as an antiinflammatory drug and antiarthritic agent. It was used for the treatment of trigeminal neuralgia.

Originator

Approval Year

PubMed

Title	Date	PubMed
Trigeminal neuralgia treated with cuprelone.	1948 Oct 30	18888679
A case of trigeminal neuralgia treated with cuproallyl-thiourea-sodium-benzoate.	1951 Sep	14873976
The role of the anaesthetist in the treatment of tic douloureux.	1955 Jul	13239940

Patents

Sample Use Guides

In Vivo Use Guide

Cuprelone (Allocupreide) has been tried in 100 mg doses intravenously twice weekly for a month.

Route of Administration: Intravenous

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:16:08 GMT 2023` Edited by `admin` on `Fri Dec 15 16:16:08 GMT 2023`
Record UNII	WKG854RBET
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ALLOCUPREIDE SODIUM

Official Name

English

ALLOCUPREIDE SODIUM [MI]

Common Name

English

CUPRALYL SODIUM

Common Name

English

BENZOIC ACID, 3-(((2-PROPEN-1-YLAMINO)THIOXOMETHYL)AMINO)-, COPPER(1+) SODIUM SALT (1:1:1)

Systematic Name

English

EBESAL

Brand Name

English

allocupreide sodium [INN]

Common Name

English

SODIUM 3-(3-ALLYL-S-CUPROPSEUDOTHIOUREIDO)BENZOATE

Common Name

English

CUPRELON

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257