U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2023
446
Substance Class Protein
Created
by admin
on Wed Apr 02 06:21:13 GMT 2025
Edited
by admin
on Wed Apr 02 06:21:13 GMT 2025
Protein Type FC FUSION PROTEIN
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
WH7BHQ0RB4
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
efanesoctocog alfa [INN]
Preferred Name English
Efanesoctocog Alfa
INN  
Official Name English
Blood coagulation factor VIII (human A1A2 domain plus B domain 5-amino acid-containing fragment) fusion protein with 288AE-XTEN (synthetic 291-amino acid linker) fusion protein with blood coagulation factor VIII (human A3C1C2 domain-containing fragment)
Systematic Name English
Efanesoctocog alfa [WHO-DD]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 591217
Created by admin on Wed Apr 02 06:21:13 GMT 2025 , Edited by admin on Wed Apr 02 06:21:13 GMT 2025
Code System Code Type Description
CAS
2252477-42-0
Created by admin on Wed Apr 02 06:21:13 GMT 2025 , Edited by admin on Wed Apr 02 06:21:13 GMT 2025
PRIMARY
NCI_THESAURUS
C174933
Created by admin on Wed Apr 02 06:21:13 GMT 2025 , Edited by admin on Wed Apr 02 06:21:13 GMT 2025
PRIMARY
SMS_ID
100000181893
Created by admin on Wed Apr 02 06:21:13 GMT 2025 , Edited by admin on Wed Apr 02 06:21:13 GMT 2025
PRIMARY
FDA UNII
WH7BHQ0RB4
Created by admin on Wed Apr 02 06:21:13 GMT 2025 , Edited by admin on Wed Apr 02 06:21:13 GMT 2025
PRIMARY
INN
11314
Created by admin on Wed Apr 02 06:21:13 GMT 2025 , Edited by admin on Wed Apr 02 06:21:13 GMT 2025
PRIMARY
DAILYMED
WH7BHQ0RB4
Created by admin on Wed Apr 02 06:21:13 GMT 2025 , Edited by admin on Wed Apr 02 06:21:13 GMT 2025
PRIMARY
Glycosylation Link Type Site
N 1_41
N 1_239
N 1_1198
N 1_1506
N 1_1797
N 2_94
N 2_384
Related Record Type Details
Antihemophilic factor (recombinant), Fc-VWF-XTEN fusion protein-EHTL
SUB_CONCEPT->SUBSTANCE
Related Record Type Details
Efanesoctocog Alfa
ACTIVE MOIETY
For hemophilia A patients
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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