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Details

Stereochemistry ACHIRAL
Molecular Formula C7H4O6S.2Na
Molecular Weight 262.148
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DISODIUM SULFOSALICYLATE

SMILES

[Na+].[Na+].OC1=CC=C(C=C1C([O-])=O)S([O-])(=O)=O

InChI

InChIKey=CSVUNXDXKHELCR-UHFFFAOYSA-L
InChI=1S/C7H6O6S.2Na/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10;;/h1-3,8H,(H,9,10)(H,11,12,13);;/q;2*+1/p-2

HIDE SMILES / InChI

Molecular Formula C7H4O6S
Molecular Weight 216.168
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Sulfosalicylic acid dihydrate is a polyfunctional metal chelating ligand that may be used as a metal scavenger.to form metal coordination complexes. Sulfosalicylic acid forms proton-transfer dye complexes with diazo compounds such as 4-(phenyldiazenyl)aniline. Proteins are precipitated upon complexation with 5-Sulfosalicylic acid, allowing the qualitative analysis of the resultant turbidity formed in a sample by these complexes leaving solution. Protein precipitation with 5-Sulfosalicylic acid has also been employed as a preparative measure for removing proteins prior to chromatographic analysis.

Approval Year

PubMed

PubMed

TitleDatePubMed
Acetaminophen induces apoptosis in rat cortical neurons.
2010-12-10
Identification of protonation state by XPS, solid-state NMR, and DFT: characterization of the nature of a new theophylline complex by experimental and computational methods.
2010-11-11
Salts of aromatic amines: crystal structures, spectroscopic and non-linear optical properties.
2010-11
Nigericin-mediated liposome loading of topotecan: is nigericin a potential drug release regulator?
2010-10-31
Polynuclear complexes of macrocyclic oxamide with 5-sulfosalicylate: syntheses, crystal structures and magnetic properties.
2010-10-28
A simple colorimetric FIA method for the determination of pyrite oxidation rates.
2010-10-15
2-Amino-5-bromo-pyridinium 3-carb-oxy-4-hy-droxy-benzene-sulfonate.
2010-08-28
Simultaneous stacking of cationic and anionic compounds in single run capillary zone electrophoresis by two-end field amplified sample injection.
2010-08-27
2-Amino-5-chloro-pyridinium 3-carb-oxy-4-hy-droxy-benzene-sulfonate.
2010-08-18
2-Amino-5-methyl-pyridinium 3-carb-oxy-4-hy-droxy-benzene-sulfonate.
2010-07-31
2-Amino-4-methyl-pyridinium 3-carb-oxy-4-hy-droxy-benzene-sulfonate monohydrate.
2010-07-24
[Hydrogen bis-(1,2,4-triazole)] 1,2,4-triazolium bis-(3-carb-oxy-4-hy-droxy-benzene-sulfonate) 1,2,4-triazole disolvate.
2010-07-17
Effect of dietary fats on oxidative-antioxidative status of blood in rats.
2010-07
Spectrum of HNF1A somatic mutations in hepatocellular adenoma differs from that in patients with MODY3 and suggests genotoxic damage.
2010-07
The T1405N carbamoyl phosphate synthetase polymorphism does not affect plasma arginine concentrations in preterm infants.
2010-05-25
Binary and Ternary Heterometallic (La3+, Gd3+, Y3+)-Eu3+ Functionalized SBA-15 Mesoporous Hybrids: Chemically Bonded Assembly and Photoluminescence.
2010-05-16
Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury.
2010-04-23
Reduction of oxidative cellular damage by overexpression of the thioredoxin TRX2 gene improves yield and quality of wine yeast dry active biomass.
2010-02-12
Reduction of ischemic and oxidative damage to the hypothalamus by hyperbaric oxygen in heatstroke mice.
2010
Guanidinium quinoline-2-carboxyl-ate.
2009-11-25
4-(2-Hydroxy-ethyl)anilinium 3-carb-oxy-4-hydroxy-benzene-sulfonate monohydrate.
2009-11-25
o-Phenyl-enediammonium bis-(3-carb-oxy-4-hydroxy-benzene-sulfonate).
2009-11-21
Hexaaqua-zinc(II) bis-(4-hydroxy-benzene-sulfonate) dihydrate.
2009-10-10
Aqua-(2-hydr-oxy-5-sulfonatobenzoato-κO)bis-(2-phenyl-1H-1,3,7,8-tetra-aza-cyclo-penta-[l]phenanthrene-κN,N)zinc(II).
2009-10-03
Proton transfer versus nontransfer in compounds of the diazo-dye precursor 4-(phenyldiazenyl)aniline (aniline yellow) with strong organic acids: the 5-sulfosalicylate and the dichroic benzenesulfonate salts, and the 1:2 adduct with 3,5-dinitrobenzoic acid.
2009-10
Resolving the role of plant glutamate dehydrogenase. I. In vivo real time nuclear magnetic resonance spectroscopy experiments.
2009-10
Removal of transition metal ions from aqueous solutions by adsorption onto a novel silica gel matrix composite adsorbent.
2009-09-30
Protective effect of transgenic expression of porcine heat shock protein 70 on hypothalamic ischemic and oxidative damage in a mouse model of heatstroke.
2009-09-03
Bismuth(III) 5-sulfosalicylate complexes: structure, solubility and activity against Helicobacter pylori.
2009-08-28
Bis[μ-1,2-bis-(1H-imidazol-1-ylmeth-yl)benzene-κN:N]disilver(I) 3-carboxyl-ato-4-hydroxy-benzene-sulfonate methanol solvate trihydrate.
2009-08-08
COOH-terminal truncations and site-directed mutations enhance thermostability and chaperone-like activity of porcine alphaB-crystallin.
2009-07-28
Pharmacokinetics of acute tryptophan depletion using a gelatin-based protein in male and female Wistar rats.
2009-07
Poly[aqua-(μ(5)-2-oxido-4-sulfonato-benzoato)lanthanum(III)].
2009-03-11
Three-dimensional networks in the 1:2 organic salts 2,2'-biimidazolium bis(3-carboxy-4-hydroxybenzenesulfonate) and 2,2'-bibenzimidazolium bis(3-carboxy-4-hydroxybenzenesulfonate) trihydrate.
2009-02
Diaqua-bis(1,10-phenanthroline-κN,N')zinc(II) 2-hydr-oxy-5-sulfonatobenzoate tetra-hydrate.
2009-01-31
3,3'-(p-Phenyl-enedimethyl-ene)di-imidazol-1-ium bis-(3-carb-oxy-4-hydroxy-benzene-sulfonate) dihydrate.
2009-01-23
Probiotics prevent intestinal barrier dysfunction in acute pancreatitis in rats via induction of ileal mucosal glutathione biosynthesis.
2009
In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II.
2008-10-15
4-(4-Carb-oxy-1,3-thia-zol-2-yl)pyridinium 3-carb-oxy-4-hydroxy-benzene-sulfonate dihydrate.
2008-09-30
Poly[[diaqua(μ(2)-4,4'-dipyridyl sulfide-κN:N')(4,4'-dipyridyl sulfide-κN)(2-hydroxy-5-sulfonatobenzoato-κO)nickel(II)] dihydrate].
2008-09-20
4,4'-Methyl-enedianilinium bis-(3-carb-oxy-4-hydroxy-benzene-sulfonate) monohydrate.
2008-09-17
1-Hydroxy-ethyl-2-methyl-5-nitro-imidazolium 3-carb-oxy-4-hydroxy-benzene-sulfonate.
2008-06-25
Pyrazine-diium bis-(3-carb-oxy-4-hydroxy-benzene-sulfonate) dihydrate.
2008-06-19
4-Carboxy-pyridinium 3-carb-oxy-4-hydroxy-benzene-sulfonate.
2008-06-07
Synthesis and characterization of conducting polyaniline 5-sulfosalicylate nanotubes.
2008-04-02
Different effects of angiotensin converting enzyme inhibitors on endothelin-1 and nitric oxide balance in human vascular endothelial cells: evidence of an oxidant-sensitive pathway.
2008
2-Carboxy-quinolinium-2,4,6-trinitro-benzene-sulfonate-quinolinium-2-carboxyl-ate (1/1/1).
2007-12-06
Tunable separation of anions and cations by column switching in ion chromatography.
2007-03-15
Comparison of the Protective Effect of Indole beta-carbolines and R-(-)-deprenyl Against Nitrogen Species-Induced Cell Death in Experimental Culture Model of Parkinson's Disease.
2005-04
Potentiometric membrane sensors based on zirconyl(IV) phthalocyanine for detection of sulfosalicylic acid.
2004-05-28
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:54:00 GMT 2025
Edited
by admin
on Mon Mar 31 18:54:00 GMT 2025
Record UNII
WFP6MAA96R
Record Status Validated (UNII)
Record Version
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Name Type Language
5-SULFOSALICYLIC ACID DISODIUM SALT
Preferred Name English
DISODIUM SULFOSALICYLATE
II  
Systematic Name English
BENZOIC ACID, 2-HYDROXY-5-SULFO-, DISODIUM SALT
Common Name English
DISODIUM SULPHOSALICYLATE
Systematic Name English
DISODIUM SULFOSALICYLATE [II]
Common Name English
DISODIUM 5-SULFOSALICYLATE
Systematic Name English
BENZOIC ACID, 2-HYDROXY-5-SULFO-, SODIUM SALT (1:2)
Common Name English
Code System Code Type Description
EVMPD
SUB170254
Created by admin on Mon Mar 31 18:54:00 GMT 2025 , Edited by admin on Mon Mar 31 18:54:00 GMT 2025
PRIMARY
RXCUI
1364465
Created by admin on Mon Mar 31 18:54:00 GMT 2025 , Edited by admin on Mon Mar 31 18:54:00 GMT 2025
PRIMARY RxNorm
SMS_ID
100000159708
Created by admin on Mon Mar 31 18:54:00 GMT 2025 , Edited by admin on Mon Mar 31 18:54:00 GMT 2025
PRIMARY
PUBCHEM
54733329
Created by admin on Mon Mar 31 18:54:00 GMT 2025 , Edited by admin on Mon Mar 31 18:54:00 GMT 2025
PRIMARY
FDA UNII
WFP6MAA96R
Created by admin on Mon Mar 31 18:54:00 GMT 2025 , Edited by admin on Mon Mar 31 18:54:00 GMT 2025
PRIMARY
EPA CompTox
DTXSID70971778
Created by admin on Mon Mar 31 18:54:00 GMT 2025 , Edited by admin on Mon Mar 31 18:54:00 GMT 2025
PRIMARY
CAS
56343-01-2
Created by admin on Mon Mar 31 18:54:00 GMT 2025 , Edited by admin on Mon Mar 31 18:54:00 GMT 2025
PRIMARY
DAILYMED
WFP6MAA96R
Created by admin on Mon Mar 31 18:54:00 GMT 2025 , Edited by admin on Mon Mar 31 18:54:00 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE