IODOACETIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C2H3IO2
Molecular Weight	185.9485
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CI

InChI

InChIKey=JDNTWHVOXJZDSN-UHFFFAOYSA-N

InChI=1S/C2H3IO2/c3-1-2(4)5/h1H2,(H,4,5)

HIDE SMILES / InChI

Molecular Formula	C2H3IO2
Molecular Weight	185.9485
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Inhibitors of caspase homologues suppress an apoptotic phenotype in cultured rabbit corpora lutea.	2001	11833936
Isolation and characterization of a novel lepidopteran-selective toxin from the venom of South Indian red scorpion, Mesobuthus tamulus.	2001	11782289
Platelet-derived growth factor-BB: a survival factor for the retinal microvasculature during periods of metabolic compromise.	2001 Aug	11840346
Effects of inhibitors on chicken polymorphonuclear leukocyte oxygenation activity measured by use of selective chemiluminigenic substrates.	2001 Feb	11926296
Moderation of iodoacetate-induced experimental osteoarthritis in rats by matrix metalloproteinase inhibitors.	2001 Nov	11795995
A novel N(alpha)-acetyl alanine aminopeptidase from Allomyces arbuscula.	2002 Apr	12106909
Catabolism of cytoplasmic and intramitochondrial adenine nucleotides in C2C12 skeletal myotube under chemical hypoxia.	2002 Apr	12014580
Substrate-dependence of reduction of MTT: a tetrazolium dye differs in cultured astroglia and neurons.	2002 Apr	11821152
Interaction of cofilin with triose-phosphate isomerase contributes glycolytic fuel for Na,K-ATPase via Rho-mediated signaling pathway.	2002 Dec 13	12359716
Mechanisms of glutamate release in the rat spinal cord slices during metabolic inhibition.	2002 Feb	11893026
Recombinant lysine:N(6)-hydroxylase: effect of cysteine-->alanine replacements on structural integrity and catalytic competence.	2002 Feb 11	11904218
Purification and properties of membrane-bound D-sorbitol dehydrogenase from Gluconobacter suboxydans IFO 3255.	2002 Jan	11866120
Glutathione peroxidase from the liver of Japanese sea bass Lateolabrax japonicus.	2002 Jan-Feb	11926531
Isolation of the patC gene encoding the cystathionine beta-lyase of Lactobacillus delbrueckii subsp. bulgaricus and molecular analysis of inter-strain variability in enzyme biosynthesis.	2002 Jul	12101291
beta-Amyloid neurotoxicity is exacerbated during glycolysis inhibition and mitochondrial impairment in the rat hippocampus in vivo and in isolated nerve terminals: implications for Alzheimer's disease.	2002 Jul	12093093
Effect of metabolic inhibition on glimepiride block of native and cloned cardiac sarcolemmal K(ATP) channels.	2002 Jul	12086984
Inhibition of plasmodium falciparum triose-phosphate isomerase by chemical modification of an interface cysteine. Electrospray ionization mass spectrometric analysis of differential cysteine reactivities.	2002 Jul 12	12006590
Identification of prolylcarboxypeptidase as the cell matrix-associated prekallikrein activator.	2002 Jul 17	12123826
Antibody to Cryptococcus neoformans capsular glucuronoxylomannan promotes expression of interleukin-12Rbeta2 subunit on human T cells in vitro through effects mediated by antigen-presenting cells.	2002 Jun	12047756
Cysteine synthase of an extremely thermophilic bacterium, Thermus thermophilus HB8.	2002 Mar	12005048
Intracellular ATP measured with luciferin/luciferase in isolated single mouse skeletal muscle fibres.	2002 Mar	11889583
ATP depletion is an important factor in DHEA-induced growth inhibition and apoptosis in BV-2 cells.	2002 Mar 15	12148690
Dinitrophenol pretreatment of rat ventricular myocytes protects against damage by metabolic inhibition and reperfusion.	2002 May	12056859
Morphological analysis of iodoacetic acid-induced cataract in the rat.	2002 May-Jun	12097793
Human, rat and chicken small intestinal Na+ - Cl- -creatine transporter: functional, molecular characterization and localization.	2002 Nov 15	12433955
[Phenomenon of pseudomutagenesis: experiments with modifiers of cell metabolism in human lymphocytes].	2002 Oct	12449644
Expression of cysteine proteinase of Clonorchis sinensis and its use in serodiagnosis of clonorchiasis.	2002 Oct	12435144
Differences between rat primary cortical neurons and astrocytes in purine release evoked by ischemic conditions.	2002 Oct	12384169
Preparation and characterization of bovine albumin isoforms.	2002 Oct 1	12297233
Glyceraldehyde metabolism in human erythrocytes in comparison with that of glucose and dihydroxyacetone.	2002 Sep	12125098
Mechanical performance and glycolytic requirement in trout ventricular muscle.	2002 Sep 1	12210119
Nucleic acid related compounds. 116. Nonaqueous diazotization of aminopurine nucleosides. Mechanistic considerations and efficient procedures with tert-butyl nitrite or sodium nitrite.	2002 Sep 20	12227811
Anandamide uptake by synaptosomes from human, mouse and rat brain: inhibition by glutamine and glutamate.	2002 Sep 3	12617751
Effects of fructose-1,6-bisphosphate on morphological and functional neuronal integrity in rat hippocampal slices during energy deprivation.	2003	12559101
Purification and some properties of cathepsin H from rabbit skeletal muscle.	2003 Apr	12565709
Glycolytic buffering affects cardiac bioenergetic signaling and contractile reserve similar to creatine kinase.	2003 Aug	12714331
Hieronymain I, a new cysteine peptidase isolated from unripe fruits of Bromelia hieronymi Mez (Bromeliaceae).	2003 Feb	12760417
Monocarboxylates and glucose utilization as energy substrates in rat brain slices under selective glial poisoning--a 31P NMR study.	2003 Feb	12701813
Glucose regulation of Saccharomyces cerevisiae cell cycle genes.	2003 Feb	12582131
The carnosine C-2 proton's chemical shift reports intracellular pH in oxidative and glycolytic muscle fibers.	2003 Feb	12541242
Volumetric and ionic responses of goldfish hepatocytes to anisotonic exposure and energetic limitation.	2003 Feb	12502772
Glycolysis and glutamate accumulation into synaptic vesicles. Role of glyceraldehyde phosphate dehydrogenase and 3-phosphoglycerate kinase.	2003 Feb 21	12488440
Novel aminopeptidase specific for glycine from Actinomucor elegans.	2003 Jan	12619677
Protein kinase C-epsilon is involved in the adenosine-activated signal transduction pathway conferring protection against ischemia-reperfusion injury in primary rat neuronal cultures.	2003 Jan	12559003
Dynamic recording of cell death in the in vitro dorsal vagal nucleus of rats in response to metabolic arrest.	2003 Jan	12522201
Pacemaker frequency is increased by sodium nitroprusside in the guinea pig gastric antrum.	2003 Jan 1	12509488
Modulation of the Pasteur effect in retinal cells: implications for understanding compensatory metabolic mechanisms.	2003 Jun	12742354
Characterization of cytotoxic and genotoxic effects of different compounds in CHO K5 cells with the comet assay (single-cell gel electrophoresis assay).	2003 Jun 6	12787820
Chemical modifications of alpha1,6-fucosyltransferase define amino acid residues of catalytic importance.	2003 Mar-Apr	12770769
Maternal diabetes in vivo and high glucose in vitro diminish GAPDH activity in rat embryos.	2003 May	12716756

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:06:14 UTC 2023` Edited by `admin` on `Fri Dec 15 15:06:14 UTC 2023`
Record UNII	WF5188V710
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IODOACETIC ACID

Systematic Name

English

IODOACETIC ACID [MI]

Common Name

English

NSC-2125

Code

English

IODOACETIC ACID [HSDB]

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID5025445