ROSOPATAMAB TETRAXETAN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 00:00:09 GMT 2025` Edited by `admin` on `Wed Apr 02 00:00:09 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	WCY6T25V3A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

rosopatamab tetraxetan [INN]

Preferred Name

English

ROSOPATAMAB TETRAXETAN

Official Name

English

DOTA-HUJ-591-GS

Common Name

English

IMMUNOGLOBULIN G1, (ANTI-(HUMAN PROSTATE-SPECIFIC ANTIGEN)) (HUMAN-MUS MUSCULUS MONOCLONAL HUJ591 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL HUJ591 .KAPPA.-CHAIN, DIMER, N6-(2-(4,7,10-TRIS(CARBOXYMETHYL)-1,4,7,10-TETRAAZACYCLODODEC-1-Y

Systematic Name

English

DOTA-HUJ-591

Common Name

English

Code System Code Type Description

INN

11334

Created by admin on Wed Apr 02 00:00:09 GMT 2025 , Edited by admin on Wed Apr 02 00:00:09 GMT 2025

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FDA UNII

WCY6T25V3A

Created by admin on Wed Apr 02 00:00:09 GMT 2025 , Edited by admin on Wed Apr 02 00:00:09 GMT 2025

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CAS

2260767-50-6

Created by admin on Wed Apr 02 00:00:09 GMT 2025 , Edited by admin on Wed Apr 02 00:00:09 GMT 2025

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NCI_THESAURUS

C174932

Created by admin on Wed Apr 02 00:00:09 GMT 2025 , Edited by admin on Wed Apr 02 00:00:09 GMT 2025

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SMS_ID

300000024162

Created by admin on Wed Apr 02 00:00:09 GMT 2025 , Edited by admin on Wed Apr 02 00:00:09 GMT 2025

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From	To
1_22	1_96
2_22	2_96
2_142	2_198
2_218	4_214
2_259	2_319
1_142	1_198
2_365	2_423
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_218	3_214
1_224	2_224
1_227	2_227
1_259	1_319
1_365	1_423

Glycosylation Link Type	Site
N	1_295
N	2_295

Related Record Type Details


					JB9647672Z

Rosopatamab tetraxetan lutetium Lu-177

LABELED -> NON-LABELED

Amount:


					2TTE6SSR0J

PARENT -> CONJUGATE

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION		RESIDUE_SPECIFIC	K		LYSINE-DOTA	KTZ0L57AI1

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL