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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Mon Mar 31 22:37:10 GMT 2025
Edited
by admin
on Mon Mar 31 22:37:10 GMT 2025
Protein Sub Type
Sequence Type COMPLETE
Record UNII
WCI46BYD7T
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ABC16
Preferred Name English
BSEP
Common Name English
BILE SALT EXPORT PUMP
Common Name English
ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 11
Common Name English
SPGP
Common Name English
PFIC2
Common Name English
ABCB11
Common Name English
PFIC-2
Common Name English
BRIC2
Common Name English
PGY4
Common Name English
Classification Tree Code System Code
UCSF-FDA TRANSPORTAL ABCB11
Created by admin on Mon Mar 31 22:37:10 GMT 2025 , Edited by admin on Mon Mar 31 22:37:10 GMT 2025
Code System Code Type Description
FDA UNII
WCI46BYD7T
Created by admin on Mon Mar 31 22:37:10 GMT 2025 , Edited by admin on Mon Mar 31 22:37:10 GMT 2025
PRIMARY
UNIPROT
O95342
Created by admin on Mon Mar 31 22:37:10 GMT 2025 , Edited by admin on Mon Mar 31 22:37:10 GMT 2025
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_109
N 1_116
N 1_122
N 1_125
Related Record Type Details
Structure of 1-(((4-((7-METHOXY-6-(SULFOOXY)-4-QUINOLINYL)OXY)PHENYL)AMINO)CARBONYL)CYCLOPROPANECARBOXYLIC ACID
INHIBITOR -> TRANSPORTER
IC50
Structure of RIFAMPIN
INHIBITOR -> TRANSPORTER
Structure of PIOGLITAZONE
INHIBITOR -> TRANSPORTER
IC50
Structure of Cyclosporine
INHIBITOR -> TRANSPORTER
Structure of PACLITAXEL
SUBSTRATE -> TRANSPORTER
Structure of VALINOMYCIN
INHIBITOR -> TRANSPORTER
Structure of GRAZOPREVIR ANHYDROUS
INHIBITOR -> TRANSPORTER
IC50
Structure of ATORVASTATIN
INHIBITOR -> TRANSPORTER
HUMAN LIVER
TISSUE EXPRESSION->TRANSPORTER
Structure of Resmetirom
INHIBITOR -> TRANSPORTER
clinical relevance of inhibition is unknown
TROGLITAZONE
INHIBITOR -> TRANSPORTER
Structure of Pralsetinib
INHIBITOR -> TRANSPORTER
Structure of Clofazimine
INHIBITOR -> TRANSPORTER
Structure of VELPATASVIR
INHIBITOR -> TRANSPORTER
IC50
Structure of RESERPINE
INHIBITOR -> TRANSPORTER
Structure of LETERMOVIR
INHIBITOR -> TRANSPORTER
Structure of VINBLASTINE
SUBSTRATE -> TRANSPORTER
Structure of BRANEBRUTINIB
INHIBITOR -> TRANSPORTER
Structure of GLYBURIDE
INHIBITOR -> TRANSPORTER
Structure of BT-070
INHIBITOR -> TRANSPORTER
Structure of PACLITAXEL
SUBSTRATE -> TRANSPORTER
Structure of LY-3509754
INHIBITOR -> TRANSPORTER
Structure of CERIVASTATIN
INHIBITOR -> TRANSPORTER
Structure of VOXILAPREVIR
SUBSTRATE -> TRANSPORTER
IC50
Structure of DUVELISIB
INHIBITOR -> TRANSPORTER
Structure of ELUXADOLINE
SUBSTRATE -> TRANSPORTER
Based on in-vitro studies, eluxadoline appears to be a substrate for OAT3, OATP1B1, BSEP, and MRP2
Structure of PRAVASTATIN
SUBSTRATE -> TRANSPORTER
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
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