25I-NBOH

COC1=CC(CCNCC2=C(O)C=CC=C2)=C(OC)C=C1I

InChIKey=FEUZHYRXGQTBRO-UHFFFAOYSA-N

InChI=1S/C17H20INO3/c1-21-16-10-14(18)17(22-2)9-12(16)7-8-19-11-13-5-3-4-6-15(13)20/h3-6,9-10,19-20H,7-8,11H2,1-2H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Serotonin 2a (5-HT2a) receptor 237 Target ID: CHEMBL224 Sources: https://www.ncbi.nlm.nih.gov/pubmed/21174090 \| https://www.ncbi.nlm.nih.gov/pubmed/24397362	Agonist 2752

PubMed

Title	Date	PubMed
Electroanalytical identification of 25I-NBOH and 2C-I via differential pulse voltammetry: a rapid and sensitive screening method to avoid misidentification.	2019-05-07	30839986
Neurochemical pharmacology of psychoactive substituted N-benzylphenethylamines: High potency agonists at 5-HT2A receptors.	2018-12	30261175
EASI-IMS an expedite and secure technique to screen for 25I-NBOH in blotter papers.	2017-10	28746793
Bad trip due to 25I-NBOMe: a case report from the EU project SPICE II plus.	2017-09	28471280
Characterization of the hepatic cytochrome P450 enzymes involved in the metabolism of 25I-NBOMe and 25I-NBOH.	2017-05	27400739
25I-NBOH: a new potent serotonin 5-HT2A receptor agonist identified in blotter paper seizures in Brazil.	2017	28706567
Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists.	2014-03-19	24397362
Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT (2A) agonist PET tracers.	2011-04	21174090
Theoretical studies on the interaction of partial agonists with the 5-HT2A receptor.	2011-01	21088982

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:41:17 GMT 2025` Edited by `admin` on `Mon Mar 31 23:41:17 GMT 2025`
Record UNII	W9G4BGW8K4
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

25I-NBOH

Preferred Name

English

Classification Tree Code System Code

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