25I-NBOH

COC1=CC(CCNCC2=CC=CC=C2O)=C(OC)C=C1I

InChIKey=FEUZHYRXGQTBRO-UHFFFAOYSA-N

InChI=1S/C17H20INO3/c1-21-16-10-14(18)17(22-2)9-12(16)7-8-19-11-13-5-3-4-6-15(13)20/h3-6,9-10,19-20H,7-8,11H2,1-2H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Serotonin 2a (5-HT2a) receptor 231 Target ID: CHEMBL224 Sources: https://www.ncbi.nlm.nih.gov/pubmed/21174090 \| https://www.ncbi.nlm.nih.gov/pubmed/24397362	Agonist 2678

PubMed

Title	Date	PubMed
Theoretical studies on the interaction of partial agonists with the 5-HT2A receptor.	2011 Jan	21088982
25I-NBOH: a new potent serotonin 5-HT(2A) receptor agonist identified in blotter paper seizures in Brazil.	2017	28706567
Characterization of the hepatic cytochrome P450 enzymes involved in the metabolism of 25I-NBOMe and 25I-NBOH.	2017 May	27400739
EASI-IMS an expedite and secure technique to screen for 25I-NBOH in blotter papers.	2017 Oct	28746793
Bad trip due to 25I-NBOMe: a case report from the EU project SPICE II plus.	2017 Sep	28471280
Neurochemical pharmacology of psychoactive substituted N-benzylphenethylamines: High potency agonists at 5-HT(2A) receptors.	2018 Dec	30261175
Electroanalytical identification of 25I-NBOH and 2C-I via differential pulse voltammetry: a rapid and sensitive screening method to avoid misidentification.	2019 May 7	30839986

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:11:33 UTC 2023` Edited by `admin` on `Sat Dec 16 11:11:33 UTC 2023`
Record UNII	W9G4BGW8K4
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

25I-NBOH

Common Name

English

Classification Tree Code System Code

WIKIPEDIA