CARBOHYDRAZIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	CH6N4O
Molecular Weight	90.0845
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NNC(=O)NN

InChI

InChIKey=XEVRDFDBXJMZFG-UHFFFAOYSA-N

InChI=1S/CH6N4O/c2-4-1(6)5-3/h2-3H2,(H2,4,5,6)

HIDE SMILES / InChI

Molecular Formula	CH6N4O
Molecular Weight	90.0845
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Loading process of sugars into cabbage petiole and asparagus shoot apex cells by incubation with hypertonic sugar solutions.	2001	11732313
Fluorimetric determination of copper(II) in aqueous solution using lucifer yellow CH as selective metal reagent.	2001 Sep	11605757
Live-cell imaging of endocytosis during conidial germination in the rice blast fungus, Magnaporthe grisea.	2002 Dec	12431458
A new synthesis of oxadiazole, thiazolidinone, N-phthalimidoamino carbonyl and arylidene derivatives with potential antimicrobial activity.	2002 Jun	12210767
Synthesis and anticancer evaluation of some new hydrazone derivatives of 2,6-dimethylimidazo[2,1-b][1,3,4]thiadiazole-5-carbohydrazide.	2003 Jul-Aug	12932910
Temperature dependence of fluid phase endocytosis coincides with membrane properties of pig platelets.	2003 Jun 10	12787933
Docking and 3-D QSAR studies on indolyl aryl sulfones. Binding mode exploration at the HIV-1 reverse transcriptase non-nucleoside binding site and design of highly active N-(2-hydroxyethyl)carboxamide and N-(2-hydroxyethyl)carbohydrazide derivatives.	2005 Jan 13	15634015
Inhibition of monoamine oxidase-A activity in rat brain by synthetic hydrazines: structure-activity relationship (SAR).	2005 Jun	16119198
Synthesis and preliminary screening of carbohydrazides and hydrazones of pyrrole derivatives as potential tuberculostatics.	2006	16572924
Synthesis and leishmanicidal activities of 1-(4-X-phenyl)-N'-[(4-Y-phenyl)methylene]-1H-pyrazole-4-carbohydrazides.	2006 Jan	16300859
Low temperature reduction of hexavalent chromium by a microbial enrichment consortium and a novel strain of Arthrobacter aurescens.	2006 Jan 25	16436214
N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists II.	2006 Nov 15	16950617
Pharmacological attenuation of Paramecium fluid-phase endocytosis.	2007	18274251
2'-(3-Hydroxy-benzyl-idene)pyrazine-2-carbohydrazide monohydrate.	2007 Dec 6	21200959
Synthesis and structure-activity relationships of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide derivatives as potential agents against A549 lung cancer cells.	2007 Nov 15	17804244
1H-Indole-3-carbaldehyde azine.	2008 Feb 6	21201898
Efficacy of nano-hydroxyapatite prepared by an aqueous solution combustion technique in healing bone defects of goat.	2008 Jun	18487940
Bis[2-hydroxy-N'-(3-phenylprop-2-enylidene)benzohydrazidato-kappa2N',O]bis(methanol-kappaO)nickel(II) and bis[2-hydroxy-N'-(3-phenylprop-2-enylidene)benzohydrazidato-kappa2N',O]bis(pyridine-kappaN)nickel(II).	2008 May	18451471
Convenient synthesis and antimicrobial activity of new 3-substituted 5-(benzofuran-2-yl)-pyrazole derivatives.	2008 Nov	18816590
N-[1-(2-Hydroxy-phen-yl)ethyl-idene]-N-(1H-indol-3-ylmethyl-ene)carbonic dihydrazide.	2008 Nov 13	21581330
P2X(7) Receptors in Neurological and Cardiovascular Disorders.	2009	20029634
Effect of oral treatment with pyrazole carbohydrazide derivatives against murine infection by Leishmania amazonensis.	2009 Apr	19346377
1-[1-(4-Chloro-phen-yl)ethyl-idene]carbono-hydrazide.	2009 Aug 12	21577542
Synthesis and antimycobacterial activity of N'-[(E)-(monosubstituted-benzylidene)]-2-pyrazinecarbohydrazide derivatives.	2009 Dec	19765866
Self-assembly of cerium-based metal-organic tetrahedrons for size-selectively luminescent sensing natural saccharides.	2009 Dec 28	20024277
EPR, mass, electronic, IR spectroscopic and thermal studies of bimetallic copper(II) complexes with tetradentate ligand, 1,4-diformyl piperazine bis(carbohydrazone).	2009 Jan	18678523
Synthesis, antichagasic in vitro evaluation, cytotoxicity assays, molecular modeling and SAR/QSAR studies of a 2-phenyl-3-(1-phenyl-1H-pyrazol-4-yl)-acrylic acid benzylidene-carbohydrazide series.	2009 Jan 1	19036592
Synthesis, characterization and properties of nitrogen-rich salts of trinitrophloroglucinol.	2009 Jan 30	18555603
1,5-Bis(2-chloro-benzyl-idene)carbonohydrazide.	2009 Jul 11	21583546
A facile synthesis of novel biologically active 4-hydroxy-N'-(benzylidene)-2H-benzo[e][1,2]thiazine-3-carbohydrazide 1,1-dioxides.	2009 Mar	18804313
Selective P2X(7) receptor antagonists for chronic inflammation and pain.	2009 Mar	18568426
1-Ethyl-N'-[(E)-4-hydroxy-benzyl-idene]-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbohydrazide.	2009 Mar 25	21582576
Synthesis and antiviral activity of beta-carboline derivatives bearing a substituted carbohydrazide at C-3 against poliovirus and herpes simplex virus (HSV-1).	2009 Nov	19647908
N'-[(E)-Benzyl-idene]-1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbohydrazide.	2009 Nov 21	21578871
Pharmacological inhibitors to identify roles of cathepsin K in cell-based studies: a comparison of available tools.	2009 Sep	19453281
(E)-1-Ethyl-4-oxo-N'-(4-pyridylmethyl-ene)-1,4-dihydroquinoline-3-carbo-hydrazide.	2009 Sep 16	21577928
Directed derivatization of organotin sulfide compounds: synthesis and self-assembly of an SnS backpack-like cage and a CuSnS ternary cluster.	2010 Jul 14	20485805
A screened hybrid density functional study on energetic complexes: cobalt, nickel and copper carbohydrazide perchlorates.	2010 Jul 15	20363561
Antiplatelet activity and structure-activity relationship study of Pyrazolopyridine Derivatives as potential series for treating thrombotic diseases.	2010 Jul 30	20523012
Schiff bases of indoline-2,3-dione (isatin) derivatives and nalidixic acid carbohydrazide, synthesis, antitubercular activity and pharmacophoric model building.	2010 Oct	20696500
Synthesis and evaluation of novel chloropyrrole molecules designed by molecular hybridization of common pharmacophores as potential antimicrobial agents.	2010 Oct 1	20800487
Novel indoline-1- or 3,4-dihydroquinoline-1(2H)-substituted carbothiohydrazides as TPO receptor agonists.	2010 Oct 1	20800483
1,5-Bis(1-phenyl-ethyl-idene)carbonohydrazide.	2010 Oct 23	21589078
1,5-Bis[1-(2,4-dihy-droxy-phen-yl)ethyl-idene]carbonohydrazide dimethyl-formamide disolvate.	2010 Oct 30	21589135
Design and synthesis of novel thiophenecarbohydrazide, thienopyrazole and thienopyrimidine derivatives as antioxidant and antitumor agents.	2010 Sep	21134865
Discovery process and characterization of novel carbohydrazide derivatives as potent and selective GHSR1a antagonists.	2010 Sep 3	20593439
1-(1-Phenyl-ethyl-idene)carbonohydrazide.	2010 Sep 30	21587659
1,5-Bis-[1-(2-hy-droxy-phen-yl)ethyl-idene]carbonohydrazide dimethyl-formamide monosolvate.	2010 Sep 30	21587616

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:45:54 GMT 2023` Edited by `admin` on `Fri Dec 15 19:45:54 GMT 2023`
Record UNII	W8V7FYY4WH
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CARBOHYDRAZIDE

Systematic Name

English

NSC-1934

Code

English

CARBOHYDRAZIDE [MI]

Common Name

English

1,3-DIAMINOUREA

Systematic Name

English

CARBONOHYDRAZIDE

Systematic Name

English

CARBONIC DIHYDRAZIDE

Systematic Name

English

Code System Code Type Description

EVMPD

SUB32902