CARBOHYDRAZIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	CH6N4O
Molecular Weight	90.0845
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NNC(=O)NN

InChI

InChIKey=XEVRDFDBXJMZFG-UHFFFAOYSA-N

InChI=1S/CH6N4O/c2-4-1(6)5-3/h2-3H2,(H2,4,5,6)

HIDE SMILES / InChI

Molecular Formula	CH6N4O
Molecular Weight	90.0845
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
1,5-Bis[1-(2,4-dihy-droxy-phen-yl)ethyl-idene]carbonohydrazide dimethyl-formamide disolvate.	2010-10-30	21589135
1,5-Bis(1-phenyl-ethyl-idene)carbonohydrazide.	2010-10-23	21589078
Synthesis and evaluation of novel chloropyrrole molecules designed by molecular hybridization of common pharmacophores as potential antimicrobial agents.	2010-10-01	20800487
Novel indoline-1- or 3,4-dihydroquinoline-1(2H)-substituted carbothiohydrazides as TPO receptor agonists.	2010-10-01	20800483
Schiff bases of indoline-2,3-dione (isatin) derivatives and nalidixic acid carbohydrazide, synthesis, antitubercular activity and pharmacophoric model building.	2010-10	20696500
1-(1-Phenyl-ethyl-idene)carbonohydrazide.	2010-09-30	21587659
1,5-Bis-[1-(2-hy-droxy-phen-yl)ethyl-idene]carbonohydrazide dimethyl-formamide monosolvate.	2010-09-30	21587616
Discovery process and characterization of novel carbohydrazide derivatives as potent and selective GHSR1a antagonists.	2010-09-03	20593439
Design and synthesis of novel thiophenecarbohydrazide, thienopyrazole and thienopyrimidine derivatives as antioxidant and antitumor agents.	2010-09	21134865
Antiplatelet activity and structure-activity relationship study of Pyrazolopyridine Derivatives as potential series for treating thrombotic diseases.	2010-07-30	20523012
A screened hybrid density functional study on energetic complexes: cobalt, nickel and copper carbohydrazide perchlorates.	2010-07-15	20363561
Directed derivatization of organotin sulfide compounds: synthesis and self-assembly of an SnS backpack-like cage and a CuSnS ternary cluster.	2010-07-14	20485805
Self-assembly of cerium-based metal-organic tetrahedrons for size-selectively luminescent sensing natural saccharides.	2009-12-28	20024277
Synthesis and antimycobacterial activity of N'-[(E)-(monosubstituted-benzylidene)]-2-pyrazinecarbohydrazide derivatives.	2009-12	19765866
N'-[(E)-Benzyl-idene]-1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbohydrazide.	2009-11-21	21578871
Synthesis and antiviral activity of beta-carboline derivatives bearing a substituted carbohydrazide at C-3 against poliovirus and herpes simplex virus (HSV-1).	2009-11	19647908
(E)-1-Ethyl-4-oxo-N'-(4-pyridylmethyl-ene)-1,4-dihydroquinoline-3-carbo-hydrazide.	2009-09-16	21577928
Pharmacological inhibitors to identify roles of cathepsin K in cell-based studies: a comparison of available tools.	2009-09	19453281
1-[1-(4-Chloro-phen-yl)ethyl-idene]carbono-hydrazide.	2009-08-12	21577542
1,5-Bis(2-chloro-benzyl-idene)carbonohydrazide.	2009-07-11	21583546
Effect of oral treatment with pyrazole carbohydrazide derivatives against murine infection by Leishmania amazonensis.	2009-04	19346377
1-Ethyl-N'-[(E)-4-hydroxy-benzyl-idene]-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbohydrazide.	2009-03-25	21582576
A facile synthesis of novel biologically active 4-hydroxy-N'-(benzylidene)-2H-benzo[e][1,2]thiazine-3-carbohydrazide 1,1-dioxides.	2009-03	18804313
Selective P2X(7) receptor antagonists for chronic inflammation and pain.	2009-03	18568426
Synthesis, characterization and properties of nitrogen-rich salts of trinitrophloroglucinol.	2009-01-30	18555603
Synthesis, antichagasic in vitro evaluation, cytotoxicity assays, molecular modeling and SAR/QSAR studies of a 2-phenyl-3-(1-phenyl-1H-pyrazol-4-yl)-acrylic acid benzylidene-carbohydrazide series.	2009-01-01	19036592
EPR, mass, electronic, IR spectroscopic and thermal studies of bimetallic copper(II) complexes with tetradentate ligand, 1,4-diformyl piperazine bis(carbohydrazone).	2009-01	18678523
P2X(7) Receptors in Neurological and Cardiovascular Disorders.	2009	20029634
N-[1-(2-Hydroxy-phen-yl)ethyl-idene]-N-(1H-indol-3-ylmethyl-ene)carbonic dihydrazide.	2008-11-13	21581330
Convenient synthesis and antimicrobial activity of new 3-substituted 5-(benzofuran-2-yl)-pyrazole derivatives.	2008-11	18816590
Efficacy of nano-hydroxyapatite prepared by an aqueous solution combustion technique in healing bone defects of goat.	2008-06	18487940
Bis[2-hydroxy-N'-(3-phenylprop-2-enylidene)benzohydrazidato-kappa2N',O]bis(methanol-kappaO)nickel(II) and bis[2-hydroxy-N'-(3-phenylprop-2-enylidene)benzohydrazidato-kappa2N',O]bis(pyridine-kappaN)nickel(II).	2008-05	18451471
Synthesis, structure elucidation and identification of antitumoural properties of novel fused 1,2,4-triazine aryl derivatives.	2008-05	17868955
1H-Indole-3-carbaldehyde azine.	2008-02-06	21201898
2'-(3-Hydroxy-benzyl-idene)pyrazine-2-carbohydrazide monohydrate.	2007-12-06	21200959
Synthesis and structure-activity relationships of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide derivatives as potential agents against A549 lung cancer cells.	2007-11-15	17804244
Carbohydrazones of substituted salicylaldehydes as potential lead compounds for the development of narrow-spectrum antimicrobials.	2007-10-05	17913061
Comparative transport efficiencies of urea analogues through urea transporter UT-B.	2007-07	17506977
Water transfer via ectomycorrhizal fungal hyphae to conifer seedlings.	2007-07	17333298
Pharmacological attenuation of Paramecium fluid-phase endocytosis.	2007	18274251
N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists II.	2006-11-15	16950617
Multinuclear magnetic resonance, electrospray ionization-mass spectroscopy, and parametric method 5 studies of a new derivative of gossypol with 2-thiophenecarbohydrazide as well as its complexes with LI+, Na+, K+, RB+, and Cs+ cations.	2006-10-15	16741985
Carbonic anhydrase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozymes I and II with some 1,3,4-oxadiazole-thiols.	2006-08	17059166
Effect of organic additives on the mitigation of volatility of 1-nitro-3,3'-dinitroazetidine (TNAZ): next generation powerful melt cast able high energy material.	2006-06-30	16310944
Low temperature reduction of hexavalent chromium by a microbial enrichment consortium and a novel strain of Arthrobacter aurescens.	2006-01-25	16436214
Synthesis and leishmanicidal activities of 1-(4-X-phenyl)-N'-[(4-Y-phenyl)methylene]-1H-pyrazole-4-carbohydrazides.	2006-01	16300859
Synthesis and preliminary screening of carbohydrazides and hydrazones of pyrrole derivatives as potential tuberculostatics.	2006	16572924
Inhibition of monoamine oxidase-A activity in rat brain by synthetic hydrazines: structure-activity relationship (SAR).	2005-06	16119198
Docking and 3-D QSAR studies on indolyl aryl sulfones. Binding mode exploration at the HIV-1 reverse transcriptase non-nucleoside binding site and design of highly active N-(2-hydroxyethyl)carboxamide and N-(2-hydroxyethyl)carbohydrazide derivatives.	2005-01-13	15634015
Studies on lead-free initiators: synthesis, characterization and performance evaluation of transition metal complexes of carbohydrazide.	2004-09-10	15363514

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:56:16 GMT 2025` Edited by `admin` on `Mon Mar 31 19:56:16 GMT 2025`
Record UNII	W8V7FYY4WH
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-1934

Preferred Name

English

CARBOHYDRAZIDE

Systematic Name

English

CARBOHYDRAZIDE [MI]

Common Name

English

1,3-DIAMINOUREA

Systematic Name

English

CARBONOHYDRAZIDE

Systematic Name

English

CARBONIC DIHYDRAZIDE

Systematic Name

English

Code System Code Type Description

EVMPD

SUB32902